Results 91 to 100 of about 5,252,193 (310)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
AntioxidantsNicotine-induced oxidative stress contributes significantly to vascular endothelial dysfunction. While negative air ions (NAIs) demonstrate potential blood-pressure-regulating and antioxidant properties, their mechanistic role remains unclear. This study
Sha Xiao +8 more
doaj +1 more source
Frontiers in Physiology, 2019 Pesticide resistance is a serious problem that poses a major challenge to pest control. One of the most potent resistance mechanisms is the overexpression of genes coding for detoxification enzymes.
Guang-Hui Tang +23 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Advanced ScienceRealgar, an arsenic‐containing traditional Chinese medicine, is commonly used in clinical practice. However, prolonged, excessive, or uncontrolled administration of Chinese patent medicines containing realgar can occasionally induce adverse effects ...
Ping Ye +7 more
doaj +1 more source
Кардиоваскулярная терапия и профилактика, 2019 Aim. To evaluate the main results of work of specialized stroke units and departments and implementation of educational campaigns on secondary stroke prevention in Tyumen district in 2011-2017.Material and methods.
D. I. Lebedeva +6 more
doaj +1 more source
Raja Bandung Banana (Musa ParadisiacaL.cv Raja Bandung) Prevents Increased Systolic Blood Pressure in Rats Given Acute Stress Test [PDF]
, 2015 The relationships between stress and hypertension have been evaluated. Heightened blood pressure (BP) reactions to acute stress have been implicated in cardiovascular disease's development. Consumption of fruit or vegetables lowering BP. This study aimed
Anindyah, D. S. (Dina) +1 more
core +2 more sources
Stress corrosion cracking control measures [PDF]
, 1977 From Abstract: "This publication attempts to diminish the incidence of stress corrosion failures by assembling the available practical measures to avoid or minimize the problem and present these measures in a form comprehensible to those persons responsible for the design, fabrication, and maintenance of new structures."
openaire +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Advanced ScienceGenetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic aromatic hydrocarbon (PAH) carcinogen.
Mingming Shan +9 more
doaj +1 more source