Results 121 to 130 of about 5,252,193 (310)

Psychopathological verbal expression of self-perceived stress in three groups of psychotic patients [PDF]

, 1997
Producción CientíficaSelf-perceived stress in 293 psychotic patients (schizophrenic, toxic and brief reactive psychoses) and a control group of 40 sane individuáis was evaluated by means of the Frankfurt Complaint Questionnaire.
Jimeno Bulnes, Natalia, Jimeno Valdés, Agustín, López Fernández, María Nieves, Vargas Aragón, Martín Lorenzo   +3 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Investigation of a method for measuring hair cortisol

Safety and Health at Work, 2022
Kento Nishi, Hiroto Izumi, Seichi Horie
doaj   +1 more source

UCP2 as a Cancer Target through Energy Metabolism and Oxidative Stress Control. [PDF]

Int J Mol Sci, 2022
Luby A, Alves-Guerra MC.
europepmc   +1 more source

Actuated rheology of magnetic micro-swimmers suspensions : emergence of motor and brake states

, 2018
We study the effect of magnetic field on the rheology of magnetic micro-swimmers suspensions. We use a model of a dilute suspension under simple shear and subjected to a constant magnetic field.
Clément, Eric, Douarche, Carine, Vincenti, Benoit   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Exposure to BDE-209 triggers necroptosis by activating the JAK2/STAT3 signaling pathway, thereby exacerbating neuroinflammation

Ecotoxicology and Environmental Safety
Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, are extensively employed in industrial applications. Among these, decabromodiphenyl ether (BDE-209), the predominant congener, is widely incorporated into consumer materials ...
Jing Yang, Liujiangshan Jiang, Haonan Ma, Yapei Zhu, Xuan Zhao, Tianyao Yang, Wei Liu   +6 more
doaj   +1 more source

The Effect of Interaction with Therapy Horses on University Students\u27 Perceived Stress Level [PDF]

, 2017
This research project investigates how university students are affected by interacting with therapy horses. Stress is the factor that will be evaluated in this particular study.
Chapman, Alexa
core   +2 more sources

Effect of oxygen plasma on nanomechanical silicon nitride resonators

, 2017
Precise control of tensile stress and intrinsic damping is crucial for the optimal design of nanomechanical systems for sensor applications and quantum optomechanics in particular.
Foelske-Schmitz, Annette, Jachimowicz, Artur, Luhmann, Niklas, Sadeghi, Pedram, Sauer, Markus, Schalko, Johannes, Schmid, Silvan   +6 more
core   +2 more sources