Results 51 to 60 of about 2,006,397 (268)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Frontiers in Physiology, 2019 Carotenoids play many crucial roles in organisms. Recently, the de novo synthesis of carotenoids has been reported in pea aphid (Acyrthosiphon pisum) through horizontally transferred genes.
Bi-Yue Ding +11 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Scientific ReportsThis study investigates the incidence of Class B respiratory infectious diseases (RIDs) in China under the Coronavirus disease 2019 (COVID-19) epidemic and examines variations post-epidemic, following the relaxation of non-pharmaceutical interventions ...
Nan Wu +6 more
doaj +1 more source
The miR-125a-5p/IRF4 Axis Mediates Sodium Arsenite-Induced M2 Macrophage Polarization
BiomoleculesArsenic, a ubiquitous metalloid, is commonly found in surface waters; as well as serious human health issues, it also induces systemic diseases and carcinogenesis upon chronic exposure.
Yan Yu +6 more
doaj +1 more source
New framework for the development of clinical guidelines in Russia
Фармакоэкономика, 2019 Aim - based on the existing regulations and recent documents from the regulatory bodies, determine the methodology for the development of clinical guidelines (CG) that meet the requirements of the legislation in the Russian Federation.Materials and ...
D. V. Blinov +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
BMC Public HealthObjective To analyze the trends in cancer burden attributable to smoking and alcohol consumption in Liaoning Province from 2008 to 2019. Methods Data on smoking and alcohol consumption were obtained from the Liaoning Provincial Chronic Disease and ...
Li Liu +12 more
doaj +1 more source
Use of Mebix in psychiatry and general medicine: relevance, prospects, case studies
Клинический разбор в общей медицинеAnxiety disorders, except the manifestations of anxiety itself, are characterized by a broad spectrum of cognitive and somatic symptoms significantly reducing the individual’s quality of life and increasing the risk of somatic disorders.
Olga V. Kotova +3 more
doaj +1 more source
Stress corrosion cracking control measures [PDF]
, 1977 From Abstract: "This publication attempts to diminish the incidence of stress corrosion failures by assembling the available practical measures to avoid or minimize the problem and present these measures in a form comprehensible to those persons responsible for the design, fabrication, and maintenance of new structures."
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