Results 61 to 70 of about 5,252,193 (310)
Trimebutine maleate in the treatment of functional biliary disorders: TRIBUNE study results
Introduction. The term «functional disorders of the biliary tract and bile ducts» defines the conditions, which produce typical patterns of biliary pains in the absence of obvious signs of organic lesions of the gallbladder and bile ducts.
V. T. Ivashkin +3 more
doaj +1 more source
PENGARUH PEMBERIAN ECHINACEA TERHADAP PERBEDAAN EKSPRESI GRANZYME DAN PERKEMBANGAN MASSA TUMOR PADA ADENOKARSINOMA MAMMA MENCIT C3H YANG MENGALAMI STRESS [PDF]
Echinacea contains some active compounds which could induce mononuclear cells activiy. Patients with breast carcinoma and stress, the immunity was depress. Echinacea will increase mononuclear cell granzyme expression.
Astanto, Teguh
core
Neural control of chronic stress adaptation [PDF]
Stress initiates adaptive processes that allow the organism to physiologically cope with prolonged or intermittent exposure to real or perceived threats. A major component of this response is repeated activation of glucocorticoid secretion by the hypothalamo-pituitary-adrenocortical (HPA) axis, which promotes redistribution of energy in a wide range of
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Background Epidemiologic researches show that short sleep duration may affect feeding behaviors resulting in higher energy intake and increased risk of obesity, but the further mechanisms that can interpret the causality remain unclear.
Tingting Du +9 more
doaj +1 more source
The Effects of Acute Stress Exposure on Neural Correlates of Pavlovian Conditioning with Monetary Gains and Losses [PDF]
Pavlovian conditioning involves the association of an inherently neutral stimulus with an appetitive or aversive outcome, such that the neutral stimulus itself acquires reinforcing properties.
Delgado, Mauricio R. +2 more
core +3 more sources
Proteotoxic Stress and Cell Lifespan Control
Eukaryotic cells continuously integrate intrinsic and extrinsic signals to adapt to the environment. When exposed to stressful conditions, cells activate compartment-specific adaptive responses. If these are insufficient, apoptosis ensues as an organismal defense line.
CENCI S, PENGO N, SITIA , ROBERTO
openaire +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Stress and the Control of Apoptosis [PDF]
Apoptotic cell death is coordinated by the caspase proteases, and these are activated via two major pathways. One of these depends upon the binding of death receptors, such as Fas (CD95) by their ligands. Alternatively, apoptosis can proceed by the activation of pro-apoptotic Bcl-2 family proteins that induce a permeabilization of the mitochondrial ...
openaire +3 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

