Results 61 to 70 of about 5,252,193 (310)

Trimebutine maleate in the treatment of functional biliary disorders: TRIBUNE study results

open access: yesМедицинский совет, 2019
Introduction. The term «functional disorders of the biliary tract and bile ducts» defines the conditions, which produce typical patterns of biliary pains in the absence of obvious signs of organic lesions of the gallbladder and bile ducts.
V. T. Ivashkin   +3 more
doaj   +1 more source

PENGARUH PEMBERIAN ECHINACEA TERHADAP PERBEDAAN EKSPRESI GRANZYME DAN PERKEMBANGAN MASSA TUMOR PADA ADENOKARSINOMA MAMMA MENCIT C3H YANG MENGALAMI STRESS [PDF]

open access: yes, 2010
Echinacea contains some active compounds which could induce mononuclear cells activiy. Patients with breast carcinoma and stress, the immunity was depress. Echinacea will increase mononuclear cell granzyme expression.
Astanto, Teguh
core  

Neural control of chronic stress adaptation [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2013
Stress initiates adaptive processes that allow the organism to physiologically cope with prolonged or intermittent exposure to real or perceived threats. A major component of this response is repeated activation of glucocorticoid secretion by the hypothalamo-pituitary-adrenocortical (HPA) axis, which promotes redistribution of energy in a wide range of
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Chronic sleep deprivation disturbs energy balance modulated by suprachiasmatic nucleus efferents in mice

open access: yesBMC Biology
Background Epidemiologic researches show that short sleep duration may affect feeding behaviors resulting in higher energy intake and increased risk of obesity, but the further mechanisms that can interpret the causality remain unclear.
Tingting Du   +9 more
doaj   +1 more source

The Effects of Acute Stress Exposure on Neural Correlates of Pavlovian Conditioning with Monetary Gains and Losses [PDF]

open access: yes, 2014
Pavlovian conditioning involves the association of an inherently neutral stimulus with an appetitive or aversive outcome, such that the neutral stimulus itself acquires reinforcing properties.
Delgado, Mauricio R.   +2 more
core   +3 more sources

Proteotoxic Stress and Cell Lifespan Control

open access: yesMolecules and Cells, 2008
Eukaryotic cells continuously integrate intrinsic and extrinsic signals to adapt to the environment. When exposed to stressful conditions, cells activate compartment-specific adaptive responses. If these are insufficient, apoptosis ensues as an organismal defense line.
CENCI S, PENGO N, SITIA , ROBERTO
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Stress and the Control of Apoptosis [PDF]

open access: yesThe Scientific World JOURNAL, 2001
Apoptotic cell death is coordinated by the caspase proteases, and these are activated via two major pathways. One of these depends upon the binding of death receptors, such as Fas (CD95) by their ligands. Alternatively, apoptosis can proceed by the activation of pro-apoptotic Bcl-2 family proteins that induce a permeabilization of the mitochondrial ...
openaire   +3 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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