Results 71 to 80 of about 2,006,397 (268)

Associations Between Urinary Phthalate Metabolites and Decreased Serum α-Klotho Level: A Cross-Sectional Study Among US Adults in Middle and Old Age

Toxics
Phthalates are widely used chemicals with ubiquitous human exposure. Evidence indicated that phthalate exposure was associated with an increased risk of aging-related diseases.
Yuyan Liu, Xiaoyu Zhao, Shuxian Ma, Yongfang Li   +3 more
doaj   +1 more source

Combat and Operational Stress Control: Application in a Burn Center. [PDF]

Eur Burn J, 2023
Cancio JM, Cancio LC.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Environmental exposure to mixtures of per- and polyfluoroalkyl substances in Northeast China: exploring links to nodular goiter and papillary thyroid carcinoma

Environmental Health
Background Environmental exposure to per- and polyfluoroalkyl substances (PFAS) has been related to some adverse health effects. An increasing number of people are suffering from nodular goiter (NG) and papillary thyroid carcinoma (PTC), the specific ...
Ziqing Sun, Boying Liu, Rui Ding, Xin Wang, Yanyan Chen, Yi Wang   +5 more
doaj   +1 more source

Agomelatine: pharmacological profile, possible application, advantages

Неврология, нейропсихиатрия, психосоматика
Agomelatine is an antidepressant with a unique pharmacological action that is both a melatonin agonist and a selective serotonin antagonist. The drug's unique pharmacological profile includes the properties of a dual 5-HT2С receptor antagonist as well as
V. E. Medvedev, O. V. Kotova, A. V. Palin, O. V. Mikheeva, E. S. Akarachkova   +4 more
doaj   +1 more source

Residual Stress Control Using Process Optimization in Directed Energy Deposition. [PDF]

Materials (Basel), 2023
Cheng M, Zou X, Pan Y, Zhou Y, Liu W, Song L.   +5 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Pain in children and adolescents

Клинический разбор в общей медицине
Pain is represented in the child and adolescent population all over the world, and many young adults have chronic pain. Chronic pain is accompanied by the lifestyle and functioning alteration, as well as by the development of depression and anxiety ...
Olga V. Kotova, Irina V. Borodulina
doaj   +1 more source

Stress control as a method to reduce perceived pain in oral lichen planus. [PDF]

Postepy Dermatol Alergol, 2023
Szymczak-Paluch M, Kłosek S.
europepmc   +1 more source