Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Diagrams in the teaching and learning of geometry: some results and ideas for future research
Diagrams are generally taken to be an integral component of doing and understanding mathematics. In the teaching and learning of geometry, the use of diagrams is not only because of the nature of geometrical objects, but also because a diagram is often a
Jones, Keith
core +1 more source
Genome-wide analysis of the <i>GATA</i> gene family in <i>Castanea mollissima</i> reveals key regulators involved in salt stress response. [PDF]
Wang X +8 more
europepmc +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Gelled Oil-in-Water Microemulsions Stabilized with Natural Surfactant Decyl Glucoside as Cutaneous Nanocarriers for Cinnamon Bark Essential Oil: Formulation and Comprehensive Pharmacotechnical Characterization. [PDF]
Živković M +12 more
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Multicomponent phase diagrams : applications for commercial aluminum alloys /
Despite decades of extensive research and application, commercial aluminum alloys are still poorly understood in terms of the phase composition and phase transformations occurring during solidification, cooling, and heating. Multicomponent Phase Diagrams:
Eskin, D. G. +2 more
core
Integrated multi-omics and machine learning identify core mechanobiology-associated immune genes in pulmonary arterial hypertension. [PDF]
Wang P, Zhao F, Yang T, Yuan Y.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source

