Results 41 to 50 of about 9,006,777 (290)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Recreational Games Program for Decreasing Post-Traumatic Stress Disorder in Mothers of Autistic Children [PDF]

International Journal of Sports Science and Arts, 2020
The current research aims to decrease post-traumatic Stress disorder in a sample of mothers of autistic children through a recreational games' Program.
Ahmed Ibrahim
doaj   +1 more source

Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress [PDF]

, 2012
Environmentally induced epigenetic alterations are related to mental health. We investigated quantitative DNA methylation status before and after an acute psychosocial stressor in two stress-related genes: oxytocin receptor (OXTR) and brain-derived ...
Dempster, E., Dempster, Emma, Unternaehrer, Eva, Lieb, Roselind, Meyer, A. H., Unternaehrer, E., Luers, P., Mill, J., Staehli, S., Hellhammer, D. H., Meyer, Andrea H., Lieb, R., Meinlschmidt, G., Staehli, Simon, Mill, John, Hellhammer, Dirk H., Meinlschmidt, Gunther, Luers P, Meinlschmidt G, Lieb R, Meyer AH, Dempster E, Staehli S, Hellhammer DH, Mill J, Unternaehrer E   +25 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Post-traumatic Stress Disorders amongpatients with Myocardial Infarction in Mosul city

Kufa Journal for Nursing Sciences, 2013
Background: Post-traumatic stress disorder (PTSD) is a severe anxiety disorder that can develop after exposure to any forms of traumatic events including myocardial infarction (MI).
Zeyad T. Al-Noimi, Eman Salem, Radhwan. H. Ibrahim   +2 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Psychiatric symptoms and emotional impact of the COVID-19 pandemic on Italian adolescents during the third lockdown: a cross-sectional cohort study

Scientific Reports, 2022
A previous study showed that about 80% of Italian adolescents reported isolated symptoms of acute or post-traumatic stress during the first lockdown in Italy.
Martina Maria Mensi, Marta Iacopelli, Marika Orlandi, Luca Capone, Chiara Rogantini, Arianna Vecchio, Erica Casini, Renato Borgatti   +7 more
doaj   +1 more source

CAM and Post‐Traumatic Stress Disorder [PDF]

Evidence-Based Complementary and Alternative Medicine, 2006
In the form of the Transcendental Meditation program CAM offers a method of eliminating deep‐rooted stress, the efficacy of which has been demonstrated in several related studies. Any discussion of CAM and post‐traumatic stress disorder should include a study of its application to Vietnam War Veterans in which improvements were observed on all ...
openaire   +2 more sources

Inflammation and post‐traumatic stress disorder [PDF]

Psychiatry and Clinical Neurosciences, 2019
While post‐traumatic stress disorder (PTSD) is currently diagnosed based solely on classic psychological and behavioral symptoms, a growing body of evidence has highlighted a link between this disorder and alterations in the immune and inflammatory systems.
Hiroaki Hori, Yoshiharu Kim
openaire   +2 more sources

Astrocytes in Post-traumatic Stress Disorder

Neuroscience Bulletin, 2022
Although posttraumatic stress disorder (PTSD) is on the rise, traumatic events and their consequences are often hidden or minimized by patients for reasons linked to PTSD itself. Traumatic experiences can be broadly classified into mental stress (MS) and traumatic brain injury (TBI), but the cellular mechanisms of MS- or TBI-induced PTSD remain unknown.
Li, Baoman, Zhang, Dianjun, Verkhratsky, Alexei; id_orcid 0000-0003-2592-9898   +2 more
openaire   +3 more sources