Results 161 to 170 of about 8,274,292 (305)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Effect of Medial Unicompartmental Knee Arthroplasty on Clinical Outcomes and Stress Distribution of Patellofemoral Joint. [PDF]

Orthop Surg
Ding Y, Xiong HZ, Sun KB, Zeng Y, Nie Y, Wu YG, Shen B.   +6 more
europepmc   +1 more source

A Resource-Based Approach to the Modeling and Simulation of Income Distribution: The Case of Pakistan

, 2011
Developing countries are affected by evident and persistent asymmetric income distribution. The increasing relevance of this issue to development agendas sets the need for planning tools that can support the analysis of the long-term impacts of ...
Pedercini, Matteo, Qureshi, Muhammad Azeem   +1 more
core  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Numerical assessment of failure load and soil-footing contact stress distribution for concrete foundations on cohesionless soil. [PDF]

Sci Rep
Alajlan ZS, Fayed S, Bayoumi EA, Yehia SA.   +3 more
europepmc   +1 more source

Measuring the Impact of Growth and Income Distribution on Poverty in India

, 2007
Since the economic reforms of the early 1990s, the Indian economy witnessed a rapid rise in the mean income level, and, simultaneously, changes in the distribution of income.
Dhongde, Shatakshee
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Stress distribution in three-unit implant-supported prostheses with different abutment designs: a finite element analysis. [PDF]

BMC Med Inform Decis Mak
Guney IF, Tosun B.
europepmc   +1 more source

Part-Time Wage-Gap in Germany: Evidence across the Wage Distribution

, 2016
This article uses insights from labour-market segmentation theory in order to investigate the wage differences between part-time and full-time workers in Germany at different parts of the wage distribution. This is accomplished with the use of a quintile
Pavlopoulos, Dimitris, Tõnurist, Piret
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source