Results 31 to 40 of about 3,638,288 (229)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Nonlinear Stress Fluctuation Dynamics of Sheared Disordered Wet Foam

open access: yes, 2003
Sheared wet foam, which stores elastic energy in bubble deformations, relaxes stress through bubble rearrangements. The intermittency of bubble rearrangements in foam leads to effectively stochastic drops in stress that are followed by periods of elastic
A.A. Kader   +21 more
core   +1 more source

Mechanical noise dependent Aging and Shear Banding behavior of a mesoscopic model of amorphous plasticity [PDF]

open access: yes, 2011
We discuss aging and localization in a simple "Eshelby" mesoscopic model of amorphous plasticity. Plastic deformation is assumed to occur through a series of local reorganizations.
Roux, Stéphane, Vandembroucq, Damien
core   +5 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Probability Distributions for Quantum Stress Tensors Measured in a Finite Time Interval

open access: yes, 2015
A meaningful probability distribution for measurements of a quantum stress tensor operator can only be obtained if the operator is averaged in time or in spacetime. This averaging can be regarded as a description of the measurement process.
Fewster, Christopher J., Ford, L. H.
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Failure Probabilities and Tough-Brittle Crossover of Heterogeneous Materials with Continuous Disorder

open access: yes, 1998
The failure probabilities or the strength distributions of heterogeneous 1D systems with continuous local strength distribution and local load sharing have been studied using a simple, exact, recursive method.
B. Kahng   +9 more
core   +1 more source

Trolox and ascorbic acid reduce direct and indirect oxidative stress in the IPEC-J2 cells, an in vitro model for the porcine gastrointestinal tract [PDF]

open access: yes, 2015
Oxidative stress in the small intestinal epithelium is a major cause of barrier malfunction and failure to regenerate. This study presents a functional in vitro model using the porcine small intestinal epithelial cell line IPEC-J2 to examine the effects ...
De Smet, Stefaan   +7 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Technical SWOT analysis of decentralised production for low voltage grids in Flanders [PDF]

open access: yes, 2012
The increasing energy prices, combined with high funding by the government, has resulted in a massive integration of decentralised electrical energy production units in Belgium.
Debruyne, Colin   +3 more
core  

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