Results 141 to 150 of about 2,850,431 (286)

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Therapeutic‐dose verapamil‐induced cardiogenic shock in an older patient: a case report

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Calcium channel blocker (CCB) toxicity most commonly follows deliberate overdose. However, severe toxicity at therapeutic doses may occur in susceptible individuals. Severe CCB toxicity often presents with clinical features of bradycardia, hypotension, hyperglycaemia, and lactic acidosis.
Christopher Thuring, Maria Carey, Timothy Webber, Biswadev Mitra   +3 more
wiley   +1 more source

Non‐Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In‐Hospital Mortality Risk in Sepsis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study evaluated the association between estimated plasma volume status (ePVS) and in‐hospital mortality in adult patients with sepsis from the MIMIC‐IV (v2.2) database. After excluding patients with early death, readmission, red blood cell transfusion, malignancy, or missing ePVS data, 17,403 patients meeting Sepsis‐3
Zhi‐An Si, Sheng‐Bing Xia, Yang Zou, Xiao‐Yan Wang   +3 more
wiley   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Towards Faster Fetal 3D CINE Cardiac MRI Reconstruction Using Region‐Optimized Virtual Coils (ROVir)

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and evaluate, in a feasibility study, a computationally efficient image‐reconstruction pipeline for 3D balanced steady state free precession (bSSFP) CINE fetal cardiac MRI that reduces radial streaking artifacts, increases effective temporal resolution, and improves diagnostic image quality compared with previous work ...
Marjolein Piek, Johannes Töger, Einar Heiberg, Katrin Fricke, Erik Hedström, Anthony H. Aletras   +5 more
wiley   +1 more source

Strain Rate Angle Distribution as an Indicator of Post‐Infarct Myocardial Remodeling: Proof‐of‐Concept of a Novel Application of the MRI Derived Strain Rate Tensor Field

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Left ventricular (LV) strain is an early indicator of myocardial dysfunction. However, conventional strain metrics do not fully account for the multidirectional nature of myocardial deformation. The strain rate tensor, derived from velocity‐encoded MRI, represents the time‐resolved magnitude and direction of strain rate without the ...
Lasse Totland, Bård A. Bendiksen, Einar S. Nordén, Ida Marie Hauge‐Iversen, Kaja Knudsen Bergo, Lili Zhang, Ivar Sjaastad, Emil K. S. Espe   +7 more
wiley   +1 more source

2026 focsused update incorporated into the Japanese society of echocardiography 2023 practice guidance for the implementation of stress echocardiography "stress echocardiography using the Valsalva maneuver". [PDF]

J Echocardiogr
Hirano Y, Iwano H, Ohara T, Guideline Committee of the Japanese Society of Echocardiography.   +3 more
europepmc   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

The Clinical Role and Impact of Dobutamine Stress Echocardiography in Liver Transplantation. [PDF]

Echocardiography
Lu J, Ferraro RA, Goldin G, Osgueritchian R, Knight E, Jani VP, Wang K, Chehab O, Su A, Hays AG, Gurakar A, Mukherjee M.   +11 more
europepmc   +1 more source