Results 111 to 120 of about 73,483 (258)

Resolving a Complex Neonatal Phenotype by Rapid Trio Whole‐Genome Sequencing: A De Novo 11q14.3–q22.3 Deletion and a Splicing‐Altering Synonymous ANK1 Variant

Journal of Clinical Laboratory Analysis, EarlyView.
Clinical utility of trio WGS and time metrics in a neonate with congenital anomalies and hemolytic anemia. ABSTRACT Background Neonates with complex and evolving phenotypes often lack sufficiently specific clinical features to guide targeted genetic testing.
Hyun‐Woo Lee, Ja‐Hyun Jang, Beom Hee Lee, Hee‐Jeong Youk, Eun Sun Kim, Kee Hyun Cho, Yun Sil Chang, Heui Seung Jo, Mi‐Ae Jang   +8 more
wiley   +1 more source

Topic diagnostics of coronary pathology in coronary heart disease patients by contrast stress echocardiography with dipyridamole

Кардиоваскулярная терапия и профилактика, 2005
Aim. To assess diagnostic potential of contrast stress echocardiography (CS-EchoCG) with dipyridamole in coronary heart disease (CHD) patients. Material and methods. The study included 22 patients (mean age 56.04±1.8 years) with typical CHD clinics.
S. T. Matskeplishvili, E. U. Asymbekova, E. A. Ayazyan, V. I. Ioshina, T. V. Kavtiashvili   +4 more
doaj  

Asymptomatic Giant Right Ventricular Myxoma in an Adolescent: A Rare Case Report With Favorable Surgical Outcome

Journal of Clinical Ultrasound, EarlyView.
We report a 13‐year‐old female with a giant right ventricular myxoma extending to the pulmonary trunk. The tumor was diagnosed by multimodal imaging and completely resected, with favorable short‐term outcomes. ABSTRACT Right ventricular (RV) myxomas account for < 5% of cardiac myxomas and are often asymptomatic, easily overlooked.
Aizezi Maihemu, Jin Bai, Chongjun Qi, Jian Liu   +3 more
wiley   +1 more source

Exercise stress echocardiography shows impaired left ventricular function after hospitalization with COVID‐19 without overt myocarditis: A pilot study

Physiological Reports
Usual clinical testing rarely reveals cardiac abnormalities persisting after hospitalization for COVID. Such testing may overlook residual changes causing increased adverse cardiac events post‐discharge. To clarify status post‐hospitalization, we related
Robert E. Goldstein, Edward A. Hulten, Thomas B. Arnold, Victoria M. Thomas, Andrew Heroy, Erika N. Walker, Keiko Fox, Hyun Lee, Joya Libbus, Bethelhem Markos, Maureen N. Hood, Travis E. Harrell, Mark C. Haigney   +12 more
doaj   +1 more source

Effect of Transthoracic Echocardiography on Prognosis Outcomes in Diabetic Patients With Various Cardiovascular Diseases: A Retrospective Cohort Study Based on the MIMIC‐IV Database

Journal of Clinical Ultrasound, EarlyView.
The Graphical Abstract Image shows the process and conclusion of the study based on the MIMIC‐IV database to explore the relationship between transthoracic echocardiography (TTE) examination and patient prognosis in diabetic patients with various cardiovascular diseases.
Ying‐er Feng, Cun‐jie Wang
wiley   +1 more source

Standardized MRI‐Based Quantification of Epicardial Adipose Tissue Volume: Reproducibility and Agreement With Cardiac Computed Tomography

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Epicardial adipose tissue volume (EATV) is increasingly recognized as a cardiometabolic risk marker associated with adverse outcomes. The most established approach for EATV quantification is cardiac computed tomography (CT). MRI offers a radiation‐free alternative allowing simultaneous assessment of myocardial function and tissue ...
Judith Gronwald, Svante S. Gersch, Zoé Böttiger, Clara Hagedorn, Torben Lange, Sören J. Backhaus, Sebastian Kelle, Constanze Schmidt, Karl Toischer, Andreas Schuster, Alexander Schulz   +10 more
wiley   +1 more source

Successful propranolol therapy for infantile hepatic hemangioma with cardiac failure

JPGN Reports, EarlyView.
Abstract Infantile hepatic hemangioma (IHH) can cause severe complications such as high‐output cardiac failure and growth faltering, requiring prompt diagnosis and intervention. In the absence of standardized treatment guidelines, propranolol has emerged as an effective and well‐tolerated therapy.
Fadhel Al Ateeqi, Ala K. Shaikhkhalil, Haitham Talo, Naeem Jagirdar, Mahdia AL‐Haidar   +4 more
wiley   +1 more source

METTL14 Regulates Myocardial Infarction Progression via m6A‐Dependent Modulation of OTUD1‐Mediated Deubiquitination of DUSP6

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial infarction (MI) is the most severe clinical manifestation of coronary artery diseases (CVD) and serves as a critical driver of sudden cardiac death and heart failure (HF). Its pathophysiology begins with the abrupt cessation of coronary blood flow, leading to severe ischemia and subsequent cardiomyocyte necrosis. This study aimed to
Cheng‐Cheng Wei, Ya‐Fang Shen, Jin‐Yu Zhang   +2 more
wiley   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source