Results 131 to 140 of about 3,304,931 (290)

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Exercise stress echocardiography shows impaired left ventricular function after hospitalization with COVID‐19 without overt myocarditis: A pilot study

Physiological Reports
Usual clinical testing rarely reveals cardiac abnormalities persisting after hospitalization for COVID. Such testing may overlook residual changes causing increased adverse cardiac events post‐discharge. To clarify status post‐hospitalization, we related
Robert E. Goldstein, Edward A. Hulten, Thomas B. Arnold, Victoria M. Thomas, Andrew Heroy, Erika N. Walker, Keiko Fox, Hyun Lee, Joya Libbus, Bethelhem Markos, Maureen N. Hood, Travis E. Harrell, Mark C. Haigney   +12 more
doaj   +1 more source

Effect of Pharmacologic Stress Test Results on Outcomes in Obese versus Nonobese Subjects Referred for Stress Perfusion Echocardiography

, 2016
Background Real-time contrast stress echocardiography (RTCSE) permits the simultaneous analysis of myocardial perfusion and wall motion during stress echocardiography, which has resulted in improved coronary artery disease detection.
Xie, Feng, Reverberi, Claudio, Porter, Thomas R., LORENZONI, VALENTINA, Gaibazzi, Nicola, Wu, Juefei   +5 more
core   +1 more source

Non‐Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In‐Hospital Mortality Risk in Sepsis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study evaluated the association between estimated plasma volume status (ePVS) and in‐hospital mortality in adult patients with sepsis from the MIMIC‐IV (v2.2) database. After excluding patients with early death, readmission, red blood cell transfusion, malignancy, or missing ePVS data, 17,403 patients meeting Sepsis‐3
Zhi‐An Si, Sheng‐Bing Xia, Yang Zou, Xiao‐Yan Wang   +3 more
wiley   +1 more source

Neutralization of IL‐17A Ameliorates PM2.5‐Induced Cardiac Inflammation and Fibrosis in Rats by Suppressing the TXNIP/NLRP3 Signaling Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Fine particulate matter (PM2.5) pollution is a major environmental risk factor for cardiovascular diseases. Exposure can cause cardiac inflammation and fibrosis. However, whether interleukin‐17A (IL‐17A) contributes to these effects is unclear.
An‐Shuai Ba, Meng Wu, Wei‐Chen Li, Wei‐Yi Li, Di Ma, Yu Wang, Zhen‐Zhen Chen   +6 more
wiley   +1 more source

Strain Rate Angle Distribution as an Indicator of Post‐Infarct Myocardial Remodeling: Proof‐of‐Concept of a Novel Application of the MRI Derived Strain Rate Tensor Field

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Left ventricular (LV) strain is an early indicator of myocardial dysfunction. However, conventional strain metrics do not fully account for the multidirectional nature of myocardial deformation. The strain rate tensor, derived from velocity‐encoded MRI, represents the time‐resolved magnitude and direction of strain rate without the ...
Lasse Totland, Bård A. Bendiksen, Einar S. Nordén, Ida Marie Hauge‐Iversen, Kaja Knudsen Bergo, Lili Zhang, Ivar Sjaastad, Emil K. S. Espe   +7 more
wiley   +1 more source

Rotating Frame Spin‐Lock Cardiac MRI Method at 9.4 T Can Characterize Diffuse Fibrosis in Progressing Hypertensive Heart Disease in Mice

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study aimed to investigate the applicability of rotating frame spin‐lock continuous wave (CW) T1ρ and relaxation along a fictitious field with Rank 2 (RAFF2) methods complementary to native T1 and late gadolinium enhancement (LGE) for cardiac magnetic resonance imaging (CMRI) of diffuse fibrosis in mice with advancing hypertensive
Riku Kiviluoto, Diana Törmä, Ahmed Tawfek, Aleksi J. Leikas, Eetu Räihä, Mari Merentie, Anna‐Kaisa Ruotsalainen, Seppo Ylä‐Herttuala, Elias Ylä‐Herttuala   +8 more
wiley   +1 more source

Cardiovascular and Hemodynamic Adaptations in Selective Fetal Growth Restriction: A Cohort Study of Monochorionic Twins

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In monochorionic diamniotic twins with selective fetal growth restriction (sFGR), the Gratacós type is defined by one vessel in one fetus. We asked how much cerebral, venous and myocardial divergence between co‐twins it captures. Method Single‐center combined retrospective–prospective cohort; one diagnostic examination per pregnancy.
Tanchanok Auwattanamongkol, Nisarat Phithakwatchara, Katika Nawapun, Sommai Viboonchart, Suparat Jaingam, Kanokwaroon Watananirun, Sriwipa Kaewsrinual, Tuangsit Wataganara   +7 more
wiley   +1 more source

Transplacental Flecainide and/or Digoxin for Fetal Tachyarrhythmias: Therapeutic Efficacy and Clinical Experience

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess the efficacy and safety of transplacental flecainide and/or digoxin for fetal tachyarrhythmias when sotalol is unavailable. Method We evaluated transplacental flecainide, digoxin, or combination therapy in a retrospective and prospective cohort across two Thai tertiary centers.
Mukpradab Darakamas, Sanitra Anuwutnavin, Fuanglada Tongprasert, Wisit Chankhunaphas, Kanyarat Nilto, Supaluck Kanjanauthai, Jarupim Soongswang   +6 more
wiley   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source