Results 71 to 80 of about 3,304,931 (290)

Coronary myocardial bridge imaging by stress-echocardiography and coronary adipose tissue attenuation on computed tomography angiography [PDF]

open access: yesExploration of Cardiology
Myocardial bridging is a congenital defect characterized by the course of a segment of the coronary arteries within the heart muscle most frequently affecting the left anterior descending coronary artery (LAD).
Domenico Tuttolomondo   +5 more
doaj   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang   +10 more
wiley   +1 more source

Stress Echocardiography for Assessment of Native Valvular Heart Disease

open access: yes, 2022
Stress echocardiography (SE) plays an important role along with resting transthoracic (TTE) and transesophageal echocardiography (TEE) with respect to evaluation and management of valvular heart disease [...
Beat Kaufmann, Beshoy Gabra
core   +1 more source

Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury

open access: yesAdvanced Science, EarlyView.
Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin   +16 more
wiley   +1 more source

Role of exercise echocardiography in paradoxical low gradient severe aortic stenosis

open access: yesRevista Portuguesa de Cardiologia, 2023
Jesús Peteiro   +2 more
doaj   +1 more source

Head to head comparison of stress echocardiography with exercise electrocardiography for the detection of coronary artery stenosis in women

open access: yes, 2019
Background: Exercise-stress electrocardiography (ECG) is initially recommended for the diagnosis of coronary artery disease. But its value has been questioned in women because of suboptimal diagnostic accuracy.
신길자
core   +1 more source

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng   +10 more
wiley   +1 more source

Lung water and coronary flow as complementary signals in aortic valve replacement [PDF]

open access: yesExploration of Cardiology
Pulmonary congestion and coronary microvascular dysfunction are central to hemodynamic adaptation before and after transcatheter aortic valve replacement (TAVR). This perspective proposes an exploratory, physiology-anchored framework that integrates lung
Marco Fabio Costantino   +4 more
doaj   +1 more source

Transthoracic three-dimensional echocardiography for the assessment of straddling tricuspid or mitral valves [PDF]

open access: yes, 2000
Background The advent of 3D echocardiography has provided a technique which, potentially, could afford significant additional information over conventional cross-sectional echocardiography in the assessment of patients with straddling atrioventricular ...
Anderson, RH   +3 more
core  

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

open access: yesAdvanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao   +11 more
wiley   +1 more source

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