Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Investigation of the Strain-Stress Field in Nanoscale Multilayer Systems by the Phase Plane Method. [PDF]
Materials (Basel)Belous D +3 more
europepmc +1 more source
Investigation of the Near-Tip Stress Field of a Notch Terminating at a Bi-Material Interface. [PDF]
Materials (Basel), 2021 Mieczkowski G +5 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Global residual stress field inference method for die-forging structural parts based on fusion of monitoring data and distribution prior. [PDF]
Vis Comput Ind Biomed ArtChen S +5 more
europepmc +1 more source
Analytical and Numerical Modeling of Stress Field and Fracture in Aluminum/Epoxy Interface Subjected to Laser Shock Wave: Application to Paint Stripping. [PDF]
Materials (Basel), 2022 Papadopoulos K, Tserpes K.
europepmc +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Monte Carlo Micro-Stress Field Simulations in Flax/E-Glass Composite Laminae with Non-Circular Flax Fibres. [PDF]
Polymers (Basel)Yang N +4 more
europepmc +1 more source
Spatiotemporal Evolution of Stress Field during Direct Laser Deposition of Multilayer Thin Wall of Ti-6Al-4V. [PDF]
Materials (Basel), 2021 Ivanov S +5 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source