Acta Ophthalmologica, EarlyView.Abstract To identify, describe and critically appraise studies developing and/or validating models for predicting sight‐threatening retinopathy of prematurity (ROP) in preterm infants undergoing screening in neonatal intensive care units. PubMed, Embase via Ovid, trial registers, and grey literature were searched from inception to 21 October 2025 ...
Stella Moutzouri +7 more
wiley +1 more source
Familial Co‐Aggregation of Neurodevelopmental Conditions and Childhood‐Onset Type 1 Diabetes
Acta Paediatrica, EarlyView.ABSTRACT Aim Childhood‐onset Type 1 diabetes (T1D) is associated with neurodevelopmental conditions (NDCs). We examined whether this association extends to relatives and assessed phenotypic, genetic, and environmental correlations between T1D and NDCs.
Shengxin Liu +12 more
wiley +1 more source
Stress hyperglycemia ratio (SHR) and triglyceride-glucose index (TYG) associated with renal response to finerenone in diabetic kidney disease: a retrospective cohort study. [PDF]
Front Med (Lausanne)Chen A +5 more
europepmc +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub +2 more
wiley +1 more source
Cumulative stress hyperglycemia ratio exposure and dynamic trajectories reveal prognostic determinants of acute hyperlipidemic pancreatitis: an 5-year cohort study. [PDF]
Lipids Health DisChen Y +8 more
europepmc +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Impacts of stress hyperglycemia ratio on functional outcomes of ischemic stroke patients treated with intravenous thrombolysis: a population-based study. [PDF]
Front NeurolLi D +7 more
europepmc +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Fasting stress hyperglycemia ratio as a predictor of intramyocardial hemorrhage and adverse outcomes in ST-segment elevation myocardial infarction. [PDF]
Front Endocrinol (Lausanne)Zhao H +8 more
europepmc +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source