Results 141 to 150 of about 1,779,603 (314)

La experiencia de sufrimiento en cuidadores principales de pacientes con dolor oncológico y no oncológico A experiência de sofrimento em cuidadores principais de pacientes com dor oncológica e não oncológica The experience of suffering in main care takers of patients with cancer-pain and non-cancer pain

open access: yesAvances en Enfermería, 2010
El objetivo de la investigación es describir la experiencia de sufrimiento de los cuidadores informales de pacientes con dolor oncológico y no oncológico de tres instituciones de salud de Medellín. Es una investigación cualitativa de tipo fenomenológico.
ALICIA KRIKORIAN D   +4 more
doaj  

Self-reported Experiences of Students with Autism Spectrum Disorder in Higher Education: A Population-based Sample [PDF]

open access: yes, 2020
Postsecondary education functions as the gateway to a host of positive adult outcomes, including financial independence, employment opportunities, and independent living.
Baczewski, Lauren Marie
core  

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

Prosocial Behavior as a Stress Moderator: The Physiological and Psychological Components [PDF]

open access: yes, 2018
Stress is a major part of everyday life for the majority of people, especially college students. Stress has a physiological response and serves an important purpose in the body.
Vannelli, Jessica
core   +1 more source

Psychological Stress = PhysiologicalStress?

open access: yes, 2022
<jats:p> Abstract. The present study analyzed experimentally the association between the experience of psychological stress and the physiological stress response of prospective teachers. The experienced stress was assessed by self-reported data. Cortisol concentrations via saliva samples reflected the physiological response.
Ditzen, Beate   +3 more
openaire   +2 more sources

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

open access: yesAdvanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan   +11 more
wiley   +1 more source

The clinically relevant MEK inhibitor mirdametinib combined with D-cycloserine and prediction error disrupts fear memory in PTSD models

open access: yesTranslational Psychiatry
This study establishes mirdametinib as the first MEK inhibitor that can undergo clinical development for psychiatric indications such as post-traumatic stress disorder (PTSD).
Sanket B. Raut   +7 more
doaj   +1 more source

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

open access: yesAdvanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini   +8 more
wiley   +1 more source

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