Results 251 to 260 of about 1,779,603 (314)

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Enhancing wellness: a systematic review of biofeedback interventions for healthcare professionals. [PDF]

Front Psychiatry
Cantone E, Urban A, Perra A, Cossu G, Tusconi M, Dursun SM, Carta MG.   +6 more
europepmc   +1 more source

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

Animal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong, Wei Qian, Deji Song, Kang Li, Li Zhang, Li Shi   +5 more
wiley   +1 more source

A latent profile analysis of physical activity participation patterns and mental health among university students: the mediating role of emotion regulation. [PDF]

Sci Rep
Chen L, Ke W, Li G, Chen J.
europepmc   +1 more source

Psychoinflammation: a conceptual framework for peripheral inflammatory phenotypes in mental health. [PDF]

Front Psychiatry
Kazgan Kılıçaslan A.
europepmc   +1 more source

The influence mechanism of mindfulness training on college students' psychological stress regulation: a mediation model with moderating effect. [PDF]

Front Public Health
Yang H, Chen F, Wei L.
europepmc   +1 more source

How digital stress affects academic procrastination and subjective well-being: mediating effect of ego depletion. [PDF]

BMC Psychol
Acaray A.
europepmc   +1 more source

Psychological adaptation mechanisms of athletes' cognitive resilience in high-temperature environments. [PDF]

Front Psychol
Guan H, Gao S.
europepmc   +1 more source