Results 71 to 80 of about 7,015,259 (298)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

The Nature of Reality: Human Stress Recovery during Exposure to Biodiverse, Multisensory Virtual Environments

open access: yesInternational Journal of Environmental Research and Public Health, 2019
Immersive virtual environments (IVEs) were used to test the effects of biodiversity on recovery from induced stress. Three natural environments and one urban environment were used to represent ordinal levels of biodiversity (none, low, moderate, and high)
Morgan F. Schebella   +3 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The impact of developmental timing for stress and recovery

open access: yesNeurobiology of Stress, 2015
Stress can have lasting effects on the brain and behavior. Delineating the impact of stress on the developing brain is fundamental for understanding mechanisms through which stress induces persistent effects on behavior that can lead to psychopathology. The growing field of translational developmental neuroscience has revealed a significant role of the
Dylan G. Gee, B.J. Casey
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Bridging childhood to adulthood: the impact of early life stress on acute stress responses

open access: yesFrontiers in Psychiatry
BackgroundChildhood trauma exerts enduring impacts on the physical and psychological well-being of individuals in adulthood, influencing their daily functioning.
Zheng Huang   +11 more
doaj   +1 more source

Physiological stress response in Nile tilapia (Oreochromis niloticus) exposed to firework noise [PDF]

open access: yesAnais da Academia Brasileira de Ciências
In the present study, impacts of firework noise on physiological response and stress recovery were investigated in Nile tilapia (Oreochromis niloticus).
HALIT KUSKU, MURAT YIGIT
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Sounds of Nature in the City: No Evidence of Bird Song Improving Stress Recovery

open access: yesInternational Journal of Environmental Research and Public Health, 2019
Noise from city traffic is one of the most significant environmental stressors. Natural soundscapes, such as bird songs, have been suggested to potentially mitigate or mask noise. All previous studies on masking noise use self-evaluation data rather than
M. Hedblom   +5 more
semanticscholar   +1 more source

Does Cardiorespiratory Fitness Buffer Stress Reactivity and Stress Recovery in Police Officers? A Real-Life Study

open access: yesFrontiers in Psychiatry, 2020
High levels of cardiorespiratory fitness have the potential to buffer against physical and mental health impairments, which can result from exposure to occupational stress.
René Schilling   +6 more
semanticscholar   +1 more source

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