Results 171 to 180 of about 10,906,859 (385)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

STRESS REDUCTION FACTOR FOR FATIGUE ASSESSMENT OF HIGHWAY BRIDGES

, 1987
Chitoshi MIKI, Toshiyasu Toyofuku, Yoji YOSHIMURA, Jun Murakoshi   +3 more
openalex   +2 more sources

REDUCTION OF STRESS—A NEW THERAPEUTIC GOAL IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE? [PDF]

, 2000
Viktor E. Eysselein
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Evaluating the Impact of Architectural Physical Elements on Reducing Stress in Surgical Patients: A Case Study in Razi Hospital, Birjand [PDF]

بیمارستان
Background and purpose: The physical and environmental characteristics of hospital spaces play a crucial role in influencing patient stress levels, particularly before and after surgery.
Elaheh Torabi, Reza Mirzaei, Ahmad Heydari, Jalil Jarrahi Feriz   +3 more
doaj  

Effect of cathodic reduction treatment on the stress corrosion cracking susceptibility of austenitic stainless steel.

, 1986
Takayoshi YAGASAKI, Yuji Kimura, Takeshi KUNIO   +2 more
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Psychological and Behavioral Benefits of a Stress/Type A Behavior Reduction Program for Healthy Middle-Aged Army Officers

, 1991
Maurizio Fava, Andrew Litrman, Peter Halperin, Eileen Pratr, Frederick R. Drews, Marvin A. Oleshansky, Joseph J. Knapik, Cara Thompson, Chris Bielenda   +8 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

The Meta-Lax method of stress reduction in welds. Phase 2 study

, 1992
Sullivan Smith
openalex   +2 more sources