Results 61 to 70 of about 681,192 (283)
Scale-dependence of lithological control on topography: Bedrock channel geometry and catchment morphometry in western Scotland [PDF]
, 2010 We propose that a scale-dependent topographic signature of erodibility arises due to fluvial and glacial erosion acting on different parts of the landscape at different times.
Bishop, P. +3 more
core +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Applied SciencesThis study investigates the impact of low-temperature stress-relieving treatment on the fatigue life of AlSi10Mg components produced by Laser Powder Bed Fusion (L-PBF).
Malcolm António +6 more
doaj +1 more source
Design, fabrication, and testing of silicon microgimbals for super-compact rigid disk drives [PDF]
, 1995 This paper documents results related to design optimization, fabrication process refinement, and micron-level static/dynamic testing of silicon micromachined microgimbals that have applications in super-compact computer disk drives as well as many other ...
Hsieh, Wen H. +4 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Frontiers in PsychologyObjectiveThis study aims to investigate the impact of yoga meditation on the mental health of female college students, focusing on how meditation improves emotional regulation, alleviates stress and strengthens psychological resilience.MethodsEmploying a
Lanjuan Liu +4 more
doaj +1 more source
Research on Optimization of Coal Pressure Relief Borehole Parameters under High-Stress Conditions
Geofluids, 2021 Determining the parameters of boreholes drilled for relieving pressure in coal seams is the key preventing and controlling rock bursts in boreholes of large diameter.
Heng Zhang +4 more
doaj +1 more source
Can hyper-synchrony in meditation lead to seizures? Similarities in meditative and epileptic brain states [PDF]
, 2014 Meditation is used worldwide by millions of people for relaxation and stress relief. Given sufficient practice, meditators may also experience a variety of altered states of consciousness.
Lindsay, Shane
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source