Results 121 to 130 of about 4,593,130 (335)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Role of stressors in histomoniasis transmission and development in turkeys

open access: yesJournal of Applied Poultry Research
SUMMARY: The aim of the current study was to evaluate the influence of stressors on histomoniasis development and lateral transmission of Histomonas meleagridis.
C. Fudge   +6 more
doaj   +1 more source

Focusing resource allocation-wellbeing as a tool for prioritizing interventions for communities at risk [PDF]

open access: yes
Objective: This study examined whether a wellbeing approach to resilience and adaptation would provide practical insights for prioritizing support to communities experiencing environmental and socio-economic stressors. Methods: A cross-sectional survey,
Anthony Hogan
core  

Trauma during humanitarian work: the effects on intimacy, wellbeing and PTSD-symptoms. [PDF]

open access: yes, 2019
Background: Organizations assisting refugees are over burdened with the Syrian humanitarian catastrophe and encounter diverse difficulties facing the consequences of this massive displacement.
Rizkalla, Niveen, SEGAL, Steven P.
core   +1 more source

Impacts of multiple stressors on freshwater biota across spatial scales and ecosystems

open access: yesNature Ecology & Evolution, 2020
S. Birk   +71 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Economic Stressors and the Demand for "Fattening" Foods [PDF]

open access: yes
A broad and growing literature suggests that uncertainty with respect to income, employment, and/or the financial resources necessary to buy food may cause people to gain weight.
Trenton Smith
core  

It's About Time: Learning Time and Educational Opportunity in California High Schools [PDF]

open access: yes, 2014
A new study by the UCLA Institute for Democracy, Education and Access (IDEA) found that teachers in high-poverty schools are more likely than their peers in low-poverty schools to report more time lost for academic instruction due to poor access to ...
John Rogers, Nicole Mirra
core  

Waveguides for Rydberg excitons in Cu$_\text{2}$O from strain traps

open access: yes, 2018
We investigate the formation of waveguides for Rydberg excitons in Cu$_\text{2}$O from cylindrical stressors as alternatives to optical traps. We show that the achievable potential depths can easily reach the meV and the trap frequencies the GHz regimes.
Krüger, Sjard Ole, Scheel, Stefan
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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