Results 21 to 30 of about 138,580 (269)

Sinoatrial Node Structure, Mechanics, Electrophysiology and the Chronotropic Response to Stretch in Rabbit and Mouse

open access: yesFrontiers in Physiology, 2020
The rhythmic electrical activity of the heart’s natural pacemaker, the sinoatrial node (SAN), determines cardiac beating rate (BR). SAN electrical activity is tightly controlled by multiple factors, including tissue stretch, which may contribute to ...
Eilidh A. MacDonald   +9 more
doaj   +1 more source

Cyclic stretch increases splicing noise rate in cultured human fibroblasts

open access: yesBMC Research Notes, 2011
Background Mechanical forces are known to alter the expression of genes, but it has so far not been reported whether they may influence the fidelity of nucleus-based processes.
Spatz Joachim P   +7 more
doaj   +1 more source

Stream self-purification efficiency / Reguliuoto upelio savaiminio apsivalymo efektyvumo vertinimas

open access: yesMokslas: Lietuvos Ateitis, 2015
The article identifies factors that have influence on the processes of river self-purification from biogenic substances when the stretches of the river are regulated and unregulated.
Laima Marozaitė, Valentinas Šaulys
doaj   +1 more source

Physical Biology of Axonal Damage

open access: yesFrontiers in Cellular Neuroscience, 2018
Excessive physical impacts to the head have direct implications on the structural integrity at the axonal level. Increasing evidence suggests that tau, an intrinsically disordered protein that stabilizes axonal microtubules, plays a critical role in the ...
Rijk de Rooij, Ellen Kuhl
doaj   +1 more source

Ranolazine-Mediated Attenuation of Mechanoelectric Feedback in Atrial Myocyte Monolayers

open access: yesFrontiers in Physiology, 2020
BackgroundMechanical stretch increases Na+ inflow into myocytes, related to mechanisms including stretch-activated channels or Na+/H+ exchanger activation, involving Ca2+ increase that leads to changes in electrophysiological properties favoring ...
Irene Del-Canto   +13 more
doaj   +1 more source

A dynamic stochastic model of frequency-dependent stress fiber alignment induced by cyclic stretch. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: Actin stress fibers (SFs) are mechanosensitive structural elements that respond to forces to affect cell morphology, migration, signal transduction and cell function.
Hui-Ju Hsu, Chin-Fu Lee, Roland Kaunas
doaj   +1 more source

Characterization of mechanical behavior of a porcine pulmonary artery strip using a randomized uniaxial stretch and stretch-rate protocol

open access: yesBioMedical Engineering OnLine, 2008
Background Much of the experimental work in soft tissue mechanics has been focused on fitting approximate relations for specific tissue types from aggregate data on multiple samples of the tissue.
Criscione John C, Jhun Choon-Sik
doaj   +1 more source

Azelnidipine inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch. [PDF]

open access: yesPLoS ONE, 2014
Acute aortic dissection is the most common life-threatening vascular disease, with sudden onset of severe pain and a high fatality rate. Clarifying the detailed mechanism for aortic dissection is of great significance for establishing effective ...
Jing Zhao   +7 more
doaj   +1 more source

Tensile Properties of Rubber Compounds at High Rates of Stretch

open access: yesRubber Chemistry and Technology, 1939
Abstract Stress-strain relationships and the work of extension for four rubber compounds were studied for a rate of stretching of the order of 1,000 per cent per second. This rate is sufficiently great so that the test may be considered to approach adiabatic conditions. A comparison of these data with similar data for a rate of stretching which
F.L. Roth, W.L. Holt
openaire   +1 more source

Localization of the sensory neurons and mechanoreceptors required for stretch-evoked colonic migrating motor complexes in mouse colon

open access: yesFrontiers in Physiology, 2011
The pacemaker and pattern generator that underlies the cyclical generation of spontaneous colonic migrating motor complexes (CMMCs) has recently been identified to lie within the myenteric plexus and/or muscularis externa.
Vladimir P Zagorodnyuk, Nick J Spencer
doaj   +1 more source

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