Results 61 to 70 of about 143,804 (311)
Stretch Induced Hyperexcitability of Mice Callosal Pathway
Frontiers in Cellular Neuroscience, 2015 Memory and learning are thought to result from changes in synaptic strength. Previous studies on synaptic physiology in brain slices have traditionally been focused on biochemical processes.
Anthony eFan +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Viscoelastic Cell Mechanics and actin remodelling are dependent on the rate of applied pressure [PDF]
, 2012 Background: living cells are subjected to external and internal mechanical stresses. The effects of these stresses on the deformation and subsequent biological response of the cells remains unclear. This study tested the hypothesis that the rate at which
Martin M Knight +8 more
core +1 more source
Enhancement of PC12 axonal extension via hybrid electromagnetic and mechanical stimulation
Journal of Biomechanical Science and Engineering, 2018 In this study, a hybrid electromagnetic and mechanical stimulation system that can apply an alternative current magnetic field (ACMF) and tensile strain fields on PC12 cells was developed to enhance nerve axonal extension. For the ACMF stimulation system,
Eiji NAKAMACHI +4 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Jurnal Ners, 2017 Menstruation is a period of uterine fluid discharge to endometrial detachment, often accompanied with pain called dysmenorrhea. The objective of this study was to analyze the effect of cat stretch exercise on the relief of menstrual pain and ...
Purwaningsih Purwaningsih +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene [PDF]
, 2017 We assess the effects of stretch rate on the mechanical properties of Prolene® (Ethicon, Gynecare, Somerville, NJ, USA), a knitted polypropylene mesh. Prolene®, consisting of macroporous knitted polypropylene, is considered here as a suitable proxy to ...
Ammouri, A.H., Bazi, T.M., Hamade, R.F.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source