Results 31 to 40 of about 479,689 (250)
Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis
Advanced Science, EarlyView.In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley +1 more source
Advanced Science, EarlyView.SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu +5 more
wiley +1 more source
Intestinal Atresia in PPP1R12A‐Related Urogenital and Brain Malformation Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT PPP1R12A‐related urogenital and brain malformation syndrome (UBMS) is a newly described disorder characterized by congenital anomalies primarily involving the urogenital system and the brain. We describe a preterm female neonate with multiple congenital anomalies, including type IIIb jejunal atresia, incomplete intestinal rotation, imperforate
Adriana Gomes +4 more
wiley +1 more source
Vision in Monkeys after Removal of the Striate Cortex
Nature, 1967 Monkeys deprived of their visual cortex (area 17) have been thought to be unable to discriminate much more than “total luminous energy”. In particular, they have been considered incapable of localizing visual events in space. It has now been shown that they can be trained to detect and accurately reach out for objects of certain kinds presented ...
Lawrence Weiskrantz +3 more
openaire +5 more sources
Animal Models and Experimental Medicine, EarlyView.Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li +9 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract This study investigates the occurrence of osteomyelitis in non‐avian dinosaurs, focusing on the Ibirá locality, a site with a high incidence of this pathological condition. We analyzed six new osteopathic sauropod specimens from the Upper Cretaceous of Brazil.
Tito Aureliano +3 more
wiley +1 more source
Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells
BioEssays, EarlyView.Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley +1 more source
The role of striate cortex in visual function of the cat [PDF]
The Journal of Neuroscience, 1995 We examined the contribution of area 17 to visual function in two cats whose fixation was monitored by means of scleral search coils. Ibotenic acid lesions were made within the physiologically identified representation of the lower left visual field of area 17. In a detection task in which the cats simply indicated the presence or absence of a vertical
Tatiana Pasternak, CR Olson, J Tompkins
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Neural electrodes for brain‐computer interface system: From rigid to soft
BMEMat, EarlyView.Here, we review the development trends of neural electrodes in BCI. This paper highlights the critical role of electrodes in BCI systems, analyzes the limitations of rigid electrodes, and introduces various flexible electrodes. Furthermore, we discuss application scenarios and prospects of BCI electrode technology, aiming to provide valuable references
Dan Yang +7 more
wiley +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source