Results 41 to 50 of about 14,348 (243)

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

Angewandte Chemie, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee, Sumin Son, Jeong Yeon Yoo, Ji Hyae Lee, Meehyun Chun, Seung Bum Park   +5 more
wiley   +2 more sources

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Synergy Between Photon‐to‐Phonon Pathway and Active Lattice Oxygen Enables Efficient and Stable Syngas Synthesis

Angewandte Chemie, EarlyView.
This work reports the design of a multifunctional MnOx support coupled with classic Rh catalytic centers for light‐driven dry reforming of methane. Benefiting from efficient photon‐to‐phonon conversion pathway and a dynamic OL‐OV cycle, the catalyst achieves high syngas production rates and light‐to‐chemical energy efficiency without external heating ...
Chengzhi Guo, Apoorv Jain, Junrun Feng, Xinyu Li, Xinru Li, Shuya Jia, Juncong Wang, Leirun Chen, Xinjie Luo, Xiaolei Zhang, Xiyi Li, Yang Lan   +11 more
wiley   +2 more sources

Multiscale Carbon‐Integrated Silicon Anode for Stable Cycling Under Practical Lithium‐Ion Battery Conditions

Advanced Energy Materials, EarlyView.
To overcome silicon anode instability, a hierarchical silicon/carbon composite fabricated from industrial waste via a scalable milling process is demonstrated. In‐depth post‐mortem analysis reveals how functional carbons—a CNT network and graphene shell—synergistically suppress degradation. This robust design delivers outstanding stability in practical
Young‐Ro Lee, Seong Chul Hong, Kyoungoh Kim, Jooha Park, Jihyeon Kim, Byungwook Kang, Youngsu Kim, Chaelin Lee, Soogyeong Son, Byungmo Cho, Junhyung Kim, Sang‐Gil Woo, Gwan‐Hyoung Lee, Kisuk Kang   +13 more
wiley   +1 more source

Natural Sunlight IR‐Driven Highly Efficient Synthesis of Acetaldehyde From Bioethanol Over Cu/Fe2O3

Angewandte Chemie, EarlyView.
This work reports a Cu/Fe2O3 catalyst for the conversion of bioethanol into valuable acetaldehyde and green hydrogen under both infrared (IR) light and natural sunlight. This IR‐driven system sets a new performance benchmark, with TON and initial TOF enhanced by at least one order of magnitude, enabled by a constructed IR photon‐to‐phonon channel and ...
Xiyi Li, Jiangting Zhao, Junjun Guo, Ze‐Kai Yu, Enqi Chen, Qiong Liu, Tieou Wang, Asterios Gavriilidis, Xue‐Qing Gong, Yang Lan, Junwang Tang   +10 more
wiley   +2 more sources

Pertanggungjawaban Korporasi atas Kontaminasi Celsium 137: Analisis Strict Liability di Cikande

Jurnal USM Law Review
This study aims to analyze regulatory fragmentation in the supervision of radioactive materials within Indonesia’s non-nuclear industrial sector and reconstruct the application of strict liability for corporate accountability in radioactive ...
Rahma Septiani, Sri Wahyu Handayani
doaj   +1 more source

Mapping the Innovation DNA of Agribusiness Firms: A Multi‐Method Analysis of Strategic Capabilities and Performance

Agribusiness, EarlyView.
ABSTRACT Innovation is essential for competitiveness in agribusiness facing dynamic environments. This study examines how market orientation, marketing, relational, and social capabilities influence innovation performance. Using data from 751 Spanish firms and a multi‐method approach that integrates Structural Equation Modeling (PLS‐SEM), Necessary ...
Beatriz Corchuelo Martínez‐Azúa, Alvaro Dias   +1 more
wiley   +1 more source

The Geography of Success: A Spatial Analysis of Export Intensity in the Italian Wine Industry

Agribusiness, EarlyView.
ABSTRACT This paper investigates the paradox of how Italy's fragmented, SME‐dominated wine industry achieves global export success. Moving beyond purely firm‐centric explanations, we test whether export intensity is spatially dependent, clustering geographically in regional ecosystems.
Nicolas Depetris Chauvin, Jonas Di Vita
wiley   +1 more source

Not All Agreements Are Equal: Heterogeneous Effects of RTAs on Latin American Agri‐Food Exports, 1990–2019

Agribusiness, EarlyView.
ABSTRACT Since the final decade of the 20th century, Latin American countries have increasingly regarded the signing of regional trade agreements (RTAs) as a promising strategy for expanding their exports. Within this context, the main objective of this study is to assess the impact of RTAs on agri‐food exports in Latin America over the period 1990 ...
María‐Isabel Ayuda, Ignacio Belloc, Vicente Pinilla   +2 more
wiley   +1 more source

From continuous to interruptible distillation: Flexible electric heating column architecture with fast start‐up

AIChE Journal, EarlyView.
Abstract Electrification of distillation offers a promising route to reducing scope‐1 emissions from one of the chemical industry's most energy‐intensive unit operations. However, conventional adiabatic columns are dynamically inflexible: Long, energy‐intensive start‐ups make shutdown and restart impractical under variable electricity prices and ...
Samuel Mercer, Michael Baldea
wiley   +1 more source