Results 131 to 140 of about 97,040 (311)

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky   +5 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Conflicto y Modernización en la Gran Minería del Cobre (1950-1970)

open access: yesHistoria (Santiago), 2004
Este artículo analiza el proceso de modernización en la Gran Minería del Cobre en Chile entre 1950 y 1971. En primer lugar, se examinan las causas, nacionales e internacionales, que llevaron a las empresas del cobre a introducir cambios en la forma de ...
Ángela Vergara Marshall
doaj  

Three Strikes Legislation [PDF]

open access: yes, 2014
Three Strikes and You\u27re Out ( Three Strikes ) laws mandate long sentences for certain habitual offenders, usually 25 years to life in prison for third-time violent offenders.
Chen, Elsa Y.
core  

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez   +5 more
wiley   +1 more source

Preventing Crime through Selective Incapacitation [PDF]

open access: yes
Making the length of a prison sentence conditional on an individual’s offense history is shown to be a powerful way of preventing crime. Under a law adopted in the Netherlands in 2001, prolific offenders could be sentenced to a prison term that was some ...
Vollaard, B.A.
core  

Two cases of lightning strikes resulting in Lichtenberg figures

open access: yes, 2014
Lightning strikes may cause serious injury such as burns and cardiac rhythm disorders or death through the powerful electric current. Lichtenberg figures, also known as the “picture of the lightning” are the important clues for lightning strikes.
A. Duran   +5 more
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai   +13 more
wiley   +1 more source

Reforming Three Strikes\u27 Excesses [PDF]

open access: yes, 2004
The obvious solution to curb Three Strikes’ excesses is legislative reform of the Three Strikes law. This Article explores possible legislative reform.
Vitiello, Michael
core  

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