Results 121 to 130 of about 1,841,622 (348)

Wilsonian effective potentials and closed string field theory

Journal of High Energy Physics
We investigate Wilsonian effective field theory as a model for the construction of the tachyon potential and nonperturbative vacua in closed string field theory.
Theodore Erler, Atakan Hilmi Fırat
doaj   +1 more source

Open string stub as an auxiliary string field

SciPost Physics
Witten's open string field theory with a generalized version of stubs is reformulated as a cubic string field theory using an auxiliary string field. The gauge symmetries and equations of motion as well as the associative algebra of the resulting theory ...
Harold Erbin, Atakan Hilmi Firat
doaj   +1 more source

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

Advanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen, Zhaohua Cai, Danrui Xiao, Yiping Shi, Qingqing Xiao, Min Liang, Yangjing Jiang, Yijie Huang, Feng Liang, Guo Zhou, Fei Zhuang, Xia Wang, Huanhuan Huo, Liang Fang, Qin Shao, Ben He   +15 more
wiley   +1 more source

Adding stubs to quantum string field theories

Journal of High Energy Physics
Generalizing recent work by Schnabl-Stettinger and Erbin-Fırat, we outline a universal algebraic procedure for ‘adding stubs’ to string field theories obeying the BV quantum master equation.
C. Maccaferri, R. Poletti, A. Ruffino, B. Valsesia   +3 more
doaj   +1 more source

The bosonic string on string-size tori from double field theory

Journal of High Energy Physics, 2017
We construct the effective action for toroidal compactifications of bosonic string theory from generalized Scherk-Schwarz reductions of double field theory.
Yago Cagnacci, Mariana Graña, Sergio Iguri, Carmen Nuñez   +3 more
doaj   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

String cosmology — Large-field inflation in string theory [PDF]

International Journal of Modern Physics A, 2015
This is a short review of string cosmology. We wish to connect string-scale physics as closely as possible to observables accessible to current or near-future experiments. Our possible best hope to do so is a description of inflation in string theory. The energy scale of inflation can be as high as that of Grand Unification (GUT). If this is the case,
openaire   +8 more sources

D-Branes, Tachyons, and String Field Theory [PDF]

, 2003
In these notes we provide a pedagogical introduction to the subject of tachyon condensation in Witten's cubic bosonic open string field theory. We use both the low-energy Yang-Mills description and the language of string field theory to explain the problem of tachyon condensation on unstable D-branes.
arxiv   +1 more source

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, EarlyView.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

Reprogramming the Tumor Immune Microenvironment with ICAM‐1‐Targeted Antibody‒Drug Conjugates and B7‐H3‐CD3 Bispecific Antibodies

Advanced Science, EarlyView.
Reprogramming the tumor immune microenvironment is crucial for transforming immune “cold” tumors into “hot” inflammatory tumors. The investigation reveals that the combination of ICAM‐1‐Dxd with B7‐H3‐CD3 bispecific antibodies not only demonstrates significant inhibitory effects on tumor growth and metastasis but also plays a vital role in ...
Shoubing Zhou, Mengyu Hong, Dan Zhao, Wenyu Li, Xiaolong Yuan, Yinghong Wang, Hualong Li, Yang Yang, Tengchuan Jin, Jing Pan   +9 more
wiley   +1 more source