Results 91 to 100 of about 989,586 (284)

CCL20/CXCL5 Drives Crosstalk Between Anaplastic Thyroid Cancer Stem Cells and Tumor‐Associated Macrophages to Promote Tumor Progression

open access: yesAdvanced Science, EarlyView.
This study elucidates the crosstalk between tumor‐associated macrophages (TAMs) and anaplastic thyroid cancer stem cells (ATCSCs). The findings reveal that CCL20 from THP‐1‐M2 activates the IRAK‐1/NF‐κB1/2 pathway in ATCSCs, thereby enhancing CXCL5 secretion.
Qi Liu   +11 more
wiley   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

open access: yesAdvanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi   +7 more
wiley   +1 more source

Two-loop scattering amplitudes: double-forward limit and colour-kinematics duality

open access: yesJournal of High Energy Physics, 2019
We propose new formulae for the two-loop n-point D-dimensional integrands of scattering amplitudes in Yang-Mills theory and gravity. The loop integrands are written as a double-forward limit of tree-level trivalent diagrams, and are inferred from the ...
Yvonne Geyer   +2 more
doaj   +1 more source

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

open access: yesAdvanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng   +11 more
wiley   +1 more source

Non-Riemannian geometry of M-theory

open access: yesJournal of High Energy Physics, 2019
We construct a background for M-theory that is moduli free. This background is then shown to be related to a topological phase of the E8(8) exceptional field theory (ExFT).
David S. Berman   +2 more
doaj   +1 more source

CircRNA‐mTOR Promotes Hepatocellular Carcinoma Progression and Lenvatinib Resistance Through the PSIP1/c‐Myc Axis

open access: yesAdvanced Science, EarlyView.
This study verifies that circRNA‐mTOR exhibits high expression levels in HCC and has a strong correlation with patient prognosis. Mechanistically, circRNA‐mTOR achieves this effect by facilitating the nuclear translocation of RNA‐binding protein (RBP) PSIP1 through specific binding.
Yongchang Tang   +12 more
wiley   +1 more source

A Note on Tensionless Strings in M-Theory [PDF]

open access: yesarXiv, 1996
In this article we examine the appearance of tensionless strings in M-Theory. We subsequently interpret these tensionless strings in a String Theory context. In particular, we examine tensionless strings appearing in M-Theory on $S^{1}$, M-Theory on $S^{1} / {\bf Z}_{2}$, and M-Theory on $T^{2}$; we then interpret the appearance of such strings in a ...
arxiv  

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao   +11 more
wiley   +1 more source

Monodromic strings [PDF]

open access: yesTheor.Math.Phys.139:834-845,2004, 2000
We argue that apart from the standard closed and open strings one may consider a third possibility that we call monodromic strings. The monodromic string propagating on a target looks like an ordinary open string (a mapping from a segment to the target) but its space of states is isomorphic to that of a closed string.
arxiv  

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy