Results 101 to 110 of about 1,337,825 (313)

The physics of vibrating strings [PDF]

open access: yesComputers in Physics, 1998
Nicholas Giordano   +2 more
openaire   +2 more sources

A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic Involution

open access: yesAdvanced Science, EarlyView.
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang   +11 more
wiley   +1 more source

String Theory and Particle Physics

open access: yes, 2019
In this next to last chapter of part II of this book, we finally consider how to obtain particle physics from string theory. Indeed, string theory is supposed to describe the real world, and since moreover we want to describe cosmology, we need to check whether what we obtain is consistent with the particle physics that we know, i.e., the Standard ...
openaire   +3 more sources

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

open access: yesAdvanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino   +16 more
wiley   +1 more source

BInD: Bond and Interaction‐Generating Diffusion Model for Multi‐Objective Structure‐Based Drug Design

open access: yesAdvanced Science, EarlyView.
Can a generative model design molecules that truly understand their targets? BInD, a diffusion‐based framework, co‐generates 3D molecules and their interactions with proteins by learning target‐specific interacting patterns. With knowledge‐based guidance and NCI‐driven optimization, BInD balances affinity, geometry, and drug‐likeness – pushing the ...
Joongwon Lee   +3 more
wiley   +1 more source

Observation of Magnetic Pseudogap Behavior in Phosphorus‐Doped Silicon

open access: yesAdvanced Science, EarlyView.
Phosphorus‐doped silicon presents a promising platform for quantum computing and hosts a Kondo condensate state featuring a pseudogap. Thermodynamic and magnetic resonance measurements reveal that this pseudogap behavior involves critical spin fluctuations, suggesting that overlapping Kondo clouds form a correlated coherent magnetic ground state ...
Suheon Lee   +16 more
wiley   +1 more source

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su   +13 more
wiley   +1 more source

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