Results 141 to 150 of about 1,327,280 (358)

Non-Riemannian geometry of M-theory

open access: yesJournal of High Energy Physics, 2019
We construct a background for M-theory that is moduli free. This background is then shown to be related to a topological phase of the E8(8) exceptional field theory (ExFT).
David S. Berman   +2 more
doaj   +1 more source

Chern-Simons Theory and Topological Strings

open access: yes, 2004
We review the relation between Chern-Simons gauge theory and topological string theory on noncompact Calabi-Yau spaces. This relation has made possible to give an exact solution of topological string theory on these spaces to all orders in the string ...
Marino, Marcos
core   +1 more source

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

open access: yesAdvanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng   +11 more
wiley   +1 more source

Trustworthy Inverse Molecular Design via Alignment with Molecular Dynamics

open access: yesAdvanced Science, EarlyView.
Data‐driven inverse molecular design (IMD) is a promising approach to discovering new molecules with desired properties. Despite the remarkable progress, existing IMD methods lag behind in terms of trustworthiness, as indicated by their misalignment with the ground‐truth function that models the molecular dynamics.
Kevin Tirta Wijaya   +3 more
wiley   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

open access: yesAdvanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng   +10 more
wiley   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

open access: yesAdvanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie   +8 more
wiley   +1 more source

Backgrounds in Boundary String Field Theory

open access: yes, 2009
We study the role of closed string backgrounds in boundary string field theory. Background independence requires the introduction of dual boundary fields, which are reminiscent of the doubled field formalism.
A. A. Gerasimov   +17 more
core   +1 more source

MoS2 Channel‐Enhanced High‐Density Charge Trap Flash Memory and Machine Learning‐Assisted Sensing Methodologies for Memory‐Centric Computing Systems

open access: yesAdvanced Science, EarlyView.
Driven by AI computing demands, this study investigates MoS2 channels for 3D NAND Flash to achieve high‐density, low‐power, and reliable nonvolatile memory. MoS2 enables a large memory window and lower operating voltages with low‐k tunneling layer, demonstrating endurance of 10⁴ cycles and retention of 10⁵ s. Comprehensive analyses and machine learning‐
Ki Han Kim   +7 more
wiley   +1 more source

N=2 Instanton Calculus In Closed String Background

open access: yes, 2007
In this contribution we describe how to obtain instanton effects in four dimensional gauge theories by computing string scattering amplitudes in D3/D(-1) brane systems.
Billo, Marco   +2 more
core   +1 more source

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