Results 51 to 60 of about 616,096 (295)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Subcritical String and Large N QCD

, 2010
We pursue the possibility of using subcritical string theory in 4 space-time dimensions to establish a string dual for large N QCD. In particular we study the even G-parity sector of the 4 dimensional Neveu-Schwarz dual resonance model as the natural ...
Charles B. Thorn, E. Witten, G. ’t Hooft, J. Maldacena   +3 more
core   +1 more source

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Duality of string amplitudes in a curved background

, 1992
We initiate a program to study the relationship between the target space, the spectrum and the scattering amplitudes in string theory. We consider scattering amplitudes following from string theory and quantum field theory on a curved target space, which
Henningson, Måns
core   +1 more source

Sequestering in string theory [PDF]

Journal of High Energy Physics, 2007
We study sequestering, a prerequisite for flavor-blind supersymmetry breaking in several high-scale mediation mechanisms, in compactifications of type IIB string theory. We find that although sequestering is typically absent in unwarped backgrounds, strongly warped compactifications do readily sequester.
Kachru, Shamit, McAllister, Liam, Sundrum, Raman   +2 more
openaire   +4 more sources

Instructional Design and Facilitation for Multigenerational Online Learning in Higher Education—Baby Boomers, Generation X, Millennials, and Generation Z

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Nontraditional students represent a substantial number and significant percentage of students in higher education. While these adult learners have similarities, they also span 50+ years with generational differences. At the same time, online learning is on the rise, offering opportunities and challenges for nontraditional students and those ...
Brittany Hyden, Catherine A. Cherrstrom
wiley   +1 more source

A Comment on the Stability of String Monopoles [PDF]

, 1993
In recent work a multimonopole solution of heterotic string theory was obtained. The monopoles are noted to be stable, in contrast with analogous solutions of Einstein-Maxwell or Yang-Mills-dilaton theory.
Bartnik, Bergshoeff, Bergshoeff, Bizon, Callan, Callan, Callan, Charap, Dabholkar, Dine, Duff, Duff, Felce, Gauntlett, Gross, Khuri, Khuri, Khuri, Khuri, Lavrelashvili, Lee, Ramzi R. Khuri, Sorkin, Strominger   +23 more
core   +3 more sources

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Searching for a Connection Between Matroid Theory and String Theory [PDF]

, 2002
We make a number of observations about matter-ghost string phase, which may eventually lead to a formal connection between matroid theory and string theory.
Achucarro, Aganagic, Anderson, Anderson, Awada, Banks, Birkhoff, Bland, Castro, Castro, Crapo, Dolan, Duff, Duff, Duff, Englert, Ferreira, Gamboa, Garcı́a-Compeán, Gelfand, Gopakumar, Gopakumar, Gursey, Horava, J. A. Nieto, Kauffman, Kutasov, Kutasov, MacLane, Marı́n, Martinec, Martinec, Montano, Murasugi, Nair, Nieto, Nieto, Nieto, Nieto, Ooguri, O’Loughlin, Przanowsky, Schiff, Schild, Schwarzler, Susskind, Tekin, Thistlethwaite, Tutte, Tutte, Vafa, Whitney, Witten, Witten, Witten, Zaikov, Zaikov, Zaikov, Zaslavsky, Zaslavsky   +59 more
core   +4 more sources

Exploring Dipolar Dynamics and Ionic Transport in Metal‐Organic Frameworks: Experimental and Theoretical Insights

Advanced Functional Materials, EarlyView.
In this study, the interplay of dipolar dynamics and ionic charge transport in MOF compounds is investigated. Synthesizing the novel structure CFA‐25 with integrated freely rotating dipolar groups, local and macroscopic effects, including interactions with Cs cations are explored.
Ralph Freund, Arthur Schulz, Peter Lunkenheimer, Maryana Kraft, Thomas Bergler, Harald Oberhofer, Dirk Volkmer   +6 more
wiley   +1 more source