Results 61 to 70 of about 39,454 (347)

Finite Element Application for Modified Cam Clay Model to Analyze Silty Clay Soil Under Strip Footing Using MATLAB

open access: yesJournal of Engineering and Sustainable Development, 2012
In this paper, the nonlinear behavior of soil has been studied. For this purpose, the modified Cam clay model has been employed. The foundation taken for this study is a strip footing of width (B=2.0 m) resting on the surface of silty clay soil. A two-
Adnan Qahtan Mohammed
doaj  

Numerical Evaluation of Settlement of Strip Footing Resting on Cavity and Weak Soil Profile

open access: yesPolytechnic Journal, 2021
This study numerically investigates the effects of different subsurface sources of weaknesses within a soil profile on the settlement of a strip footing using the finite element method (FEM).
Mohammed S. Hussain
doaj   +1 more source

A Shared Ontology Approach to Semantic Representation of BIM Data [PDF]

open access: yes, 2017
Architecture, engineering, construction and facility management (AEC-FM) projects involve a large number of participants that must exchange information and combine their knowledge for successful completion of a project.
Karshenas, Saeed, Niknam, Mehrdad
core   +1 more source

The SO(N) principal chiral field on a half-line [PDF]

open access: yes, 1999
We investigate the integrability of the SO(N) principal chiral model on a half-line, and find that mixed Dirichlet/Neumann boundary conditions (as well as pure Dirichlet or Neumann) lead to infinitely many conserved charges classically in involution.
Cherednik I V   +10 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Bond order wave instabilities in doped frustrated antiferromagnets: "Valence bond solids" at fractional filling

open access: yes, 2006
We explore both analytically and numerically the properties of doped t-J models on a class of highly frustrated lattices, such as the kagome and the pyrochlore lattice. Focussing on a particular sign of the hopping integral and antiferromagnetic exchange,
A. Läuchli   +4 more
core   +2 more sources

Isospin-breaking corrections in the pion-deuteron scattering length [PDF]

open access: yes, 2005
It is shown that isospin-breaking corrections to the pion-deuteron scattering length can be very large, because of the vanishing of the isospin-symmetric contribution to this scattering length at leading order in chiral perturbation theory.
A. Rusetsky   +27 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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