Results 61 to 70 of about 5,509,985 (297)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Terahertz electro-optical multi-functional modulator and its coupling mechanisms based on upper-layer double graphene ribbons and lower-layer a graphene strip

open access: yesNew Journal of Physics, 2020
A terahertz multifunction modulator composed of upper-layer double graphene ribbons and lower-layer a graphene strip, which can generate a Fano resonance produced by hybrid between a broad mode and a narrow mode, is proposed to realize electro-optical ...
Zhimin Liu   +7 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Equilibrium Shapes with Stress Localisation for Inextensible Elastic Mobius and Other Strips [PDF]

open access: yes, 2015
We formulate the problem of finding equilibrium shapes of a thin inextensible elastic strip, developing further our previous work on the Möbius strip. By using the isometric nature of the deformation we reduce the variational problem to a second-order ...
van der Heijden, GHM, Starostin, EL
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Rethinking Strip Searches by NSW Police [PDF]

open access: yes, 2019
This report investigates the adequacy of the law regulating strip searches conducted by NSW Police. The report concludes that our laws are not strong enough to protect the public from unnecessary strip searches and do not provide clear guidance to police.
Grewcock, Michael ; https://orcid.org/   +1 more
core   +2 more sources

Pseudoholomorphic strips in symplectizations II: Fredholm theory and transversality

open access: yesCommunications on Pure and Applied Mathematics, 2003
AbstractThis paper is part of a larger program, the investigation of the chord problem in three dimensional contact geometry. The main tool will be pseudoholomorphic strips in the symplectisation of a three dimensional contact manifold with two totally real submanifolds L0, L1 as boundary conditions.
openaire   +3 more sources

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

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