Results 41 to 50 of about 39,560 (308)
Microstructure-based modeling of IMC layer thickness effect on tensile behavior of Cu/Al clad strip
Materials Research Express, 2020 A microstructure-based model is proposed for quantitative estimation of tensile mechanical property of Cu/Al clad strips. In the proposed model, the fracture criterion for matrix Cu and Al, interface intermetallic compounds (IMCs) and interface between ...
Tao Sun +3 more
doaj +1 more source
Mechanical Engineering Journal, 2022 In this paper, the dynamic fracture problem of a functionally graded piezoelectric material strip (FGPM strip) containing a crack perpendicular to the interface between the FGPM strip and a homogeneous layer is considered.
Sei UEDA, Ryousuke NAKA
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Variation of microstrip impedance with strip thickness
Electronics Letters, 1969 The letter indicates the way in which the characteristic impedance of single and coupled microstrip can vary with strip thickness, and points out that, in many cases of current practical interest, in both computer-circuit and microwave technologies, such variation is too large to be ignored without giving rise to serious error.
M.A.R. Gunston, J.R. Weale
openaire +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Histogram of transverse thickness profile along the strip width direction of specimens.
, 2020 Histogram of transverse thickness profile along the strip width direction of specimens.
Hongyang Zhao (1901329) +2 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
International Journal of Smart and Nano Materials, 2019 With the capability of additive manufacturing, complex structures are easily fabricated to achieve various design purposes. In this work, a bi-material strip temperature sensor with complex periodic pattern design is purposed and investigated through ...
Baobao Tang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source