Results 61 to 70 of about 5,579,144 (303)

Assessment of additional endpoints for trials in acute stroke - what, when, where, in who?

, 2012
Functional outcome in acute stroke trials among others is usually measured on the modified Rankin Scale. However, new onset of depression, cognitive decline, and communication deficits alone or in combination affect more than 25% of patients. This report
TONI, Danilo, European Stroke Organisation Outcomes Working Group   +1 more
core   +1 more source

The challenge of acute-stroke management: does telemedicine offer a solution? [PDF]

, 2006
<p><b>Background:</b> Several studies have described successful experiences with the use of telemedicine in acute stroke. The objective of this study was to assess the feasibility, acceptability, and treatment delivery reliability, of ...
Langhorne, P., Wu, O.
core   +1 more source

Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE) [PDF]

, 2022
Background and Purpose: The association of dyslipidemia with stroke has been inconsistent, which may be due to differing associations within etiological stroke subtypes.
Wang, Xingyu, Czlonkowska, Anna, Langhorne, Peter, Malaga, German, Rao-Melacini, Purnima, Damasceno, Albertino, Yusoff, Khalid, Yusufali, Afzalhussein, Ogunniyi, Adesola, O’Donnell, Martin J., Rosengren, Annika, Hussain, Fawaz Al, Sniderman, Allan, Lanas, Fernando, Hankey, Graeme J., Oguz, Aytekin, McQueen, Matthew, Rosengren, Annika,, Ogah, Okechukwu S, Rumboldt, Zvonko, Rangarajan, Sumathy, Hankey, Graeme J, Lisheng, Liu, O’Donnell, Martin J, Avezum, Alvaro, O'Donnell, Martin J, Ogah, Okechukwu S., Diener, Hans-Christoph, Zhang, Hongye, Dans, Antonio L., Elsayed, Ahmed, Weimar, Christian, Yusuf, Salim, Lopez-Jaramillo, Patricio, Xavier, Denis, Pais, Prem, Diaz, Rafael, Ferguson, John, Iqbal, Romana, O'Donnell, Martin J., Penaherrera, Ernesto, on Behalf of the INTERSTROKE Investigators, Dans, Antonio L, Oveisgharan, Shahram, Iversen, Helle K., Pare, Guillaume, Mondo, Charles, Iversen, Helle K, Nilanont, Yongchai, Pogosova, Nana, Judge, Conor, Chin, Siu Lim, Al Hussain, Fawaz, Ryglewicz, Danuta   +53 more
core   +1 more source

The role of fasting versus nonfasting triglycerides in ischemicstroke: a systematic review

Frontiers in Neurology, 2010
Objective: To synthesize results from pertinent studies and determine if fasting and/or nonfasting triglycerides are a risk factor for ischemic stroke.
Christopher Leonards, Martin Ebinger, Martin Ebinger, Jana Batluk, Uwe Malzahn, Peter Heuschmann, Matthias Endres, Matthias Endres   +7 more
doaj   +1 more source

High-sensitivity C-reactive protein as a better predictor of post-thrombolytic functional outcome in patients with previous antiplatelet therapy

European Journal of Medical Research, 2022
Background C-reactive protein (CRP) is an important biomarker of inflammation and plays a pivotal role in predicting the clinical prognosis of cardiovascular and cerebrovascular diseases.
Tan Li, Qiannan Yu, Yiqing Wang, Xiuying Cai, Yan Kong, Hongru Zhao, Shanshan Diao, Yiren Qin, Qi Fang   +8 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Pengaruh Inovasi Jasa dan Harga terhadap Nilai yang Dirasakan Pasien di Stroke Center RS Al-Islam Bandung

Global Medical & Health Communication, 2015
Abstrak Rumah sakit sebagai salah satu industri jasa harus dapat menghasilkan produk barang maupun jasa dengan kualitas yang baik. Tujuan penelitian ini adalah ingin mengetahui pengaruh inovasi jasa dan harga pada nilai yang dirasakan pasien di Stroke ...
Siska Nia Irasanti, Yudi Azis, Wawang S. Sukarya   +2 more
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source