Results 271 to 280 of about 127,749 (338)

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang   +7 more
wiley   +1 more source

Sustainable RCCI engine operation with an ANN based novel tri-fuel approach. [PDF]

open access: yesSci Rep
Elumalai PV   +4 more
europepmc   +1 more source

Visualization Study of Misfire Phenomena under Light-Load Conditions in a 2-Stroke Engine.

open access: bronze, 1995
Taketoshi Fujikawa   +3 more
openalex   +2 more sources

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin   +10 more
wiley   +1 more source

Wireless Soft Athlete Bioelectronics for Monitoring Carbon Dioxide Ventilation and Physiological Performance

open access: yesAdvanced Science, EarlyView.
A wireless soft athlete bioelectronic system offers a real‐time continuous monitoring of various physiological signals and metabolites during exercise. Abstract Wearable devices have become essential tools for monitoring athletes' health and performance.
Tae Woog Kang   +12 more
wiley   +1 more source

Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop

open access: yesAdvanced Science, EarlyView.
The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu   +22 more
wiley   +1 more source

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