Results 41 to 50 of about 128,069 (305)
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Design and development of piston-controlled intake port for 4-stroke engine [PDF]
, 2008 In a two stroke engine, piston control the intake port opening and closing that combine the intake and compression stroke in 1800 crank rotation. The operational concept of two stroke engine is applied to the existing four stroke engine cylinder head ...
Amran, Kaharudin
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One-dimensional simulation of a 4-stroke SI engine employing novel cylinder head concept : intake and exhaust flow investigation [PDF]
, 2010 This project investigates the flow characteristic in novel cylinder head at various port size and runner length. Novel cylinder head engine is a design engine that operates in a 4-stroke operational cycle.
Corretgé Bergua, Roser +1 more
core +3 more sources
Applied Sciences, 2017 The paper presents the results of research on the turbocharged spark ignition engine with additional exhaust expansion in a separate cylinder, which is commonly known as the five-stroke engine.
Marcin Noga
doaj +1 more source
Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control
Advanced Engineering Materials, EarlyView.This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian +4 more
wiley +1 more source
A comparative study on mean value modelling of two-stroke marine diesel engine [PDF]
, 2009 In the present paper, two mean value modelling approaches of varying complexity, capable of simulating two-stroke marine Diesel engines, are presented. Both approaches were implemented in the computational environment of MATLAB Simulink®. Simulation runs
Theotokatos, Gerasimos
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WAYS TO IMPROVE EFFECTIVENESS OF ICE AS POWER UNIT OF CAR HADI-34 [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2013 The results of searching for ways to reduce fuel consumption record car HADI-34 when using a power plant subcompact four-stroke engine are given. Concluded the feasibility of changing the external high-speed performance at throttle-free regulation.The ...
Abramchuk, F. +3 more
doaj
3D‐Printed Giant Magnetoresistive (GMR) Sensors Based on Self Compliant Springs
Advanced Engineering Materials, EarlyView.This work explores 3D‐printed GMR sensors utilizing self‐compliant spring structures and conductive PLA composites. By optimizing arm width, we achieved high piezoresistive (0.34%/mm) and magnetoresistive (0.77%/mT) sensitivities. Demonstrated through Bluetooth‐integrated pressure and magnetic position sensing, these full printed low‐cost, customizable
Josu Fernández Maestu +4 more
wiley +1 more source
The digital simulation of a turbo-charged diesel engine [PDF]
, 1969 A mathematical simulation of a six cylinder four stroke water cooled diesel engine is described and then used to study the changes in performance caused by variations of engine paramters and operating conditions.
Hodgetts, D., Shroff, H. D.
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