The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Scavenge flow analysis of opposed-piston two-stroke engine based on dynamic characteristics
Opposed-piston two-stroke engine has been proposed by Beijing Institute of Technology to improve power density and complete machine balance relative to conventional engines. In order to study opposed-piston two-stroke engine scavenging flow, a scavenging
Fu-kang Ma +3 more
semanticscholar +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
The paper presents the results of research on the turbocharged spark ignition engine with additional exhaust expansion in a separate cylinder, which is commonly known as the five-stroke engine.
Marcin Noga
doaj +1 more source
A comparative study on mean value modelling of two-stroke marine diesel engine [PDF]
In the present paper, two mean value modelling approaches of varying complexity, capable of simulating two-stroke marine Diesel engines, are presented. Both approaches were implemented in the computational environment of MATLAB Simulink®. Simulation runs
Theotokatos, Gerasimos
core
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
WAYS TO IMPROVE EFFECTIVENESS OF ICE AS POWER UNIT OF CAR HADI-34 [PDF]
The results of searching for ways to reduce fuel consumption record car HADI-34 when using a power plant subcompact four-stroke engine are given. Concluded the feasibility of changing the external high-speed performance at throttle-free regulation.The ...
Abramchuk, F. +3 more
doaj
Design and development of piston-controlled intake port for 4-stroke engine [PDF]
In a two stroke engine, piston control the intake port opening and closing that combine the intake and compression stroke in 1800 crank rotation. The operational concept of two stroke engine is applied to the existing four stroke engine cylinder head ...
Amran, Kaharudin
core
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Characteristics of the Limit Cycle of a Reciprocating Quantum Heat Engine [PDF]
When a reciprocating heat engine is started it eventually settles to a stable mode of operation. The approach of a first principle quantum heat engine toward this stable limit cycle is studied.
J. Wei +5 more
core +1 more source

