Results 51 to 60 of about 1,556,072 (396)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Selected Issues of the Indicating Measurements in a Spark Ignition Engine with an Additional Expansion Process

Applied Sciences, 2017
The paper presents the results of research on the turbocharged spark ignition engine with additional exhaust expansion in a separate cylinder, which is commonly known as the five-stroke engine.
Marcin Noga
doaj   +1 more source

Design and development of piston-controlled intake port for 4-stroke engine [PDF]

, 2008
In a two stroke engine, piston control the intake port opening and closing that combine the intake and compression stroke in 1800 crank rotation. The operational concept of two stroke engine is applied to the existing four stroke engine cylinder head ...
Amran, Kaharudin
core  

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

WAYS TO IMPROVE EFFECTIVENESS OF ICE AS POWER UNIT OF CAR HADI-34 [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2013
The results of searching for ways to reduce fuel consumption record car HADI-34 when using a power plant subcompact four-stroke engine are given. Concluded the feasibility of changing the external high-speed performance at throttle-free regulation.The ...
Abramchuk, F., Vrublevskiy, F., Podlishchuk, S., Andrusishin, A.   +3 more
doaj  

The digital simulation of a turbo-charged diesel engine [PDF]

, 1969
A mathematical simulation of a six cylinder four stroke water cooled diesel engine is described and then used to study the changes in performance caused by variations of engine paramters and operating conditions.
Hodgetts, D., Shroff, H. D.
core  

Characteristics of the Limit Cycle of a Reciprocating Quantum Heat Engine [PDF]

, 2004
When a reciprocating heat engine is started it eventually settles to a stable mode of operation. The approach of a first principle quantum heat engine toward this stable limit cycle is studied.
J. Wei, L. Diósi, R. A. Fischer, R. Alicki, Ronnie Kosloff, Tova Feldmann   +5 more
core   +1 more source

Effect of Engine Speeds and Dimethyl Ether on Methyl Decanoate HCCI Combustion and Emission Characteristics Based on Low-Speed Two-Stroke Diesel Engine

Polish Maritime Research, 2020
The combustion and emission characteristics of homogeneous charge compression ignition (HCCI) fuelled by methyl decanoate (MD) with different engine speeds and dimethyl ether (DME) mixing ratios are investigated in this work.
Shiye Wang, Li Yao
semanticscholar   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source