Results 151 to 160 of about 129,018 (264)

Botulinum Toxin A in Poststroke Oromandibular Dystonia: Case Reports

open access: yesCase Reports in Neurological Medicine
Elena Brevi   +7 more
doaj   +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

open access: yesEpilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo   +91 more
wiley   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia   +4 more
wiley   +1 more source

Rethinking stroke rehabilitation in the technological age. [PDF]

open access: yesSingapore Med J
Lo YT, Tan BY, Venketasubramanian N.
europepmc   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

open access: yesExploration, EarlyView.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li   +14 more
wiley   +1 more source

Wearable Robot Boosts Muscle Recovery in Adolescents With Spinal Muscular Atrophy

open access: yesFlexTech, EarlyView.
Isokinetic training robot with a variable stiffness mechanism for juveniles with SMA type II. Credit: Yuebing Li et al./Nature. ABSTRACT Yuebing Li and colleagues developed a lightweight wearable device integrating a variable‐stiffness mechanism with a back‐drivable damping motor to deliver isokinetic resistance training for adolescents with spinal ...
Yin Huang
wiley   +1 more source

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