Results 51 to 60 of about 1,136,066 (284)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Motivating mobility: designing for lived motivation in stroke rehabilitation [PDF]

, 2011
How to motivate and support behaviour change through design is becoming of increasing interest to the CHI community. In this paper, we present our experiences of building systems that motivate people to engage in upper limb rehabilitation exercise after ...
Wilkinson, Anna, Madeline Balaam, Thomas Nind, Axelrod, Lesley, Rennick Egglestone, Stefan, Lesley Axelrod, Anna Wilkinson, Hughes, Ann-Marie, Ann-Marie Hughes, Tom Rodden, Harris, Eric, Stefan Rennick Egglestone, Nind, Thomas, Egglestone, Stefan Rennick, Geraldine Fitzpatrick, Rodden, Tom, Burridge, Jane, Ian Ricketts, Hughes, A.M., Balaam, Madeline, Mawson, Susan, Eric Harris, Susan Mawson, Ricketts, Ian, Mawson, Sue, Fitzpatrick, Geraldine, Jane Burridge   +26 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Stroke rehabilitation and patients with multimorbidity: a scoping review protocol [PDF]

, 2015
Stroke care presents unique challenges for clinicians, as most strokes occur in the context of other medical diagnoses. An assessment of capacity for implementing “best practice” stroke care found clinicians reporting a strong need for training specific ...
Anita Menon, Robert Teasell, Teasell, Robert, Dawson, Deirdre, Deirdre Dawson, Kaileah A. McKellar, Wasdell, Michael, J. Andrew McClure, Lyons, Renee F., Kara Ronald, McClure, J. Andrew, Michael Wasdell, Michelle L.A. Nelson, Linda Kelloway, Sarah Munce, McKellar, Kaileah A., Munce, Sarah, Renee F. Lyons, Nelson, Michelle L.A., Ronald, Kara, Kelloway, Linda, Menon, Anita   +21 more
core   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Translation of evidence-based Assistive Technologies into stroke rehabilitation: Users' perceptions of the barriers and opportunities [PDF]

, 2014
Background: Assistive Technologies (ATs), defined as "electrical or mechanical devices designed to help people recover movement", demonstrate clinical benefits in upper limb stroke rehabilitation; however translation into clinical practice is poor ...
Tedesco-Triccas, Lisa, Burridge, Jane Helena, Demain, S.H., Hughes, Ann-Marie, Demain, SH, Swain, Ian, Tedesco Triccas, Lisa, Swain, I, Swain, Ian D., Hughes, A-M, Meagher, Claire, Tedesco-Triccas, L., Ellis-Hill, Caroline, Burridge, J.H., Turk, R, Burridge, JH, Meagher, C., Ellis-Hill, C, Hughes, A-M., Tedesco-Triccas, L, Turk, R., Demain, Sara Holtum, Turk, Ruth, Demain, Sara H., Meagher, C   +24 more
core   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Evaluating an extended rehabilitation service for stroke patients (EXTRAS): Study protocol for a randomised controlled trial [PDF]

, 2015
Background: Development of longer term stroke rehabilitation services is limited by lack of evidence of effectiveness for specific interventions and service models.
McMeekin, P, Anne-Marie Laverty, Price, Christopher, Laverty, AM, Laverty, Anne Marie, Avril Drummond, Lisa Shaw, Christopher Price, Peter McMeekin, Rodgers, H, Hills, K, Cant, R, Cant, Robin, Drummond, Avril, McMeekin, Peter, Christopher McKevitt, Forster, A, Ford, Gary, Howel, D, Gary A Ford, Katie Hills, Shaw, L, Drummond, A, Denise Howel, Forster, Anne, McKevitt, Christopher, Ford, GA, Rodgers, Helen, Robin Cant, Helen Rodgers, Price, C, Ford, Gary A., Hills, Katie, Anne Forster, Helen Rodgers, Howel, Denise, Laverty, Anne-Marie, Shaw, Lisa, McKevitt, C   +38 more
core   +2 more sources