Results 141 to 150 of about 4,500,631 (382)

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho   +7 more
wiley   +1 more source

Atrial Contribution to Stroke Volume in Dogs with Chronic Heart Block [PDF]

open access: bronze, 1966
J. H. Snyder   +5 more
openalex   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

open access: yesAdvanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja   +6 more
wiley   +1 more source

Lesion Volume as a Predictor of Return to Work After Stroke

open access: yesCerebral Circulation - Cognition and Behavior
Introduction: Facilitating a successful return to work plays a pivotal role in reintegrating stroke survivors into the community. This study aims to explore the significance of lesion volume in the acute phase of stroke as a predictor for returning to ...
Gisle Berg Helland   +11 more
doaj   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi   +10 more
wiley   +1 more source

Outcome of Coronary Artery Bypass Grafts: Comparison between on Pump and off Pump [PDF]

open access: yesActa Medica Iranica, 2010
The present study was undertaken to compare the in hospital results of coronary artery bypass graft (CABG) with (on pump) or without (off pump) cardiopulmonary bypass (CPB).
Rasoul Ibrahim Abdulrahman   +1 more
doaj  

Carotid stenting: is there an operator effect? A pooled analysis from the carotid stenting trialists' collaboration.

open access: yes, 2013
BACKGROUND AND PURPOSE: Randomized clinical trials show higher 30-day risk of stroke or death after carotid artery stenting compared with surgery. We examined whether operator experience is associated with 30-day risk of stroke or death in the Carotid ...
Algra, A   +32 more
core   +1 more source

Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim   +5 more
wiley   +1 more source

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