Results 191 to 200 of about 4,090,604 (368)

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

Advanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou, Chao Dong, Xiaochun Shen, Pengbo Wang, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Chengxiang Xu, Kaipeng Duan, Dongbao Li, Jin Zhou   +11 more
wiley   +1 more source

Comparação entre a ecocardiografia 2D e 3D na avaliação do remodelamento reverso após a TRC Comparación entre la ecocardiografía 2D y 3D en la evaluación del remodelado reverso después de la TRC Comparison between 2D and 3D echocardiography in the evaluation of reverse remodeling after CRT

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: A ecocardiografia consiste em método muito útil para seleção e avaliação de resposta à terapia de ressincronização cardíaca (TRC). O eco 3D já tem seu papel estabelecido na avaliação dos volumes ventriculares e fração de ejeção ventricular ...
Viviane Tiemi Hotta, Martino Martinelli Filho, Charles Mady, Wilson Mathias Jr., Marcelo L.C. Vieira   +4 more
doaj  

Effect of goal-directed fluid therapy based on both stroke volume variation and delta stroke volume on the incidence of composite postoperative complications among individuals undergoing meningioma resection. [PDF]

Chin Med J (Engl), 2023
Feng S, Xiao W, Zhang Y, Ma Y, Yang S, He T, Wang T.   +6 more
europepmc   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

Advanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu, Chengya Huang, Xin Li, Haonan Yu, Yuefeng Xia, Kun Liu, Xingji You, Jingxiang Wu   +7 more
wiley   +1 more source

Relations of Stroke Volume and Cardiac Output to Body Composition [PDF]

, 2001
Tarquin Collis, Richard B. Devereux, Mary J. Roman, Giovanii de Simone, Jeun-Liang Yeh, Barbara V. Howard, Richard R. Fabsitz, Thomas K. Welty   +7 more
openalex   +1 more source

CNPY2 Aggravates Renal Tubular Cell Ferroptosis in Diabetic Nephropathy by Regulating PERK/ATF4/CHAC1 Pathway and MAM Integrity

Advanced Science, EarlyView.
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen, Dongwei Liu, Lei Lei, Ting Liu, Shaokang Pan, Hui Wang, Yong Liu, Yingjin Qiao, Zhangsuo Liu, Qi Feng   +9 more
wiley   +1 more source

Resilient and Flexible Electrohydrodynamics Pumps for Human–Machine Interfaces

Advanced Science, EarlyView.
This study introduces resilient and flexible electrohydrodynamic (EHD) pumps designed to enhance human–machine interfaces. These pumps are both quiet and compact, featuring a unique electrode configuration that overcomes the typical limitations associated with dielectric breakdowns and subsequent permanent failures.
Yu Kuwajima, Amr Marzuq, Soraya Segawa, Yuya Yamaguchi, Yuhei Yamada, Takafumi Morita, Katrene Morozov, Haruto Iwasaki, Sota Suzuki, Hiroyuki Nabae, Vito Cacucciolo, Naoki Hosoya, Yasuaki Kakehi, Shingo Maeda   +13 more
wiley   +1 more source

Lateral Ventricle Volume from Computed Tomography Scans Is Correlated with Pre-Stroke Impairment and Post-Stroke Cognitive Performance

Cerebral Circulation - Cognition and Behavior
Introduction: The link between neurodegenerative disease and stroke is well established and there is a need to understand pre-morbid brain anatomy to explain between-subject differences.
Till Schellhorn, Elakkyen Murugesu, Karoline Skogen, Eva Aamodt, Atle Bjørnerud, Mona Beyer, Ingvild Saltvedt, Bradley MacIntosh   +7 more
doaj  

Reliability of pulse pressure and stroke volume variation in assessing fluid responsiveness in the operating room: a metanalysis and a metaregression. [PDF]

Crit Care, 2023
Messina A, Caporale M, Calabrò L, Lionetti G, Bono D, Matronola GM, Brunati A, Frassanito L, Morenghi E, Antonelli M, Chew MS, Cecconi M.   +11 more
europepmc   +1 more source

Micro‐Coil Neuromodulation at Single‐Cell and Circuit Levels for Inhibiting Natural Neuroactivity, Neutralizing Electric Neural Excitation, and Suppressing Seizures

Advanced Science, EarlyView.
Micromagnetic stimulation (µMS) offers a precise method for neural inhibition, complementing existing neuromodulation techniques. Using an implantable micro‐coil device, µMS selectively suppresses cortical activity with high spatial resolution. It effectively counteracts micro‐electrode stimulation and reduces seizure amplitude, highlighting its ...
Kayeon Kim, Xiyuan Liu, Bingdong Chang, Guanghui Li, Gwendoline A. E. Anand, Su Genelioglu, Alexandra Katherine Isis Yonza, Andrew J Whalen, Rune W Berg, Shelley I Fried, Anpan Han, Changsi Cai   +11 more
wiley   +1 more source