Results 241 to 250 of about 779,727 (355)

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source

Reduced Stroke Volume and Brain Perfusion Drive Postural Hyperventilation in Postural Orthostatic Tachycardia Syndrome. [PDF]

JACC Basic Transl Sci
Baker JR, Incognito AV, Ranada SI, Sheldon RS, Sharkey KA, Phillips AA, Wilson RJA, Raj SR.   +7 more
europepmc   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

How to Reliably Measure Stroke Volume Index in Pulmonary Arterial Hypertension: A Comparison of Thermodilution, Direct and Indirect Fick, and Cardiac MRI. [PDF]

Life (Basel)
Baccelli A, Gopalan D, Davies RJ, Haji G, Gin-Sing W, Howard LS, Lo Giudice F.   +6 more
europepmc   +1 more source

Effects of Acute Hypoxia at Moderate Altitude on Stroke Volume and Cardiac Output During Exercise

, 2010
Taira Fukuda, Taketeru Maegawa, Akihiro Matsumoto, Yutaka Komatsu, Toshiaki Nakajima, Ryozo Nagai, Takashi Kawahara   +6 more
openalex   +2 more sources

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Low Stroke Volume Predicts Deterioration in Intermediate-Risk Pulmonary Embolism: Prospective Study. [PDF]

West J Emerg Med
Weekes AJ, Hambright P, Trautmann A, Ali S, Pikus A, Wellinsky N, Shah S, O'Connell N.   +7 more
europepmc   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Stroke volume variation remains accurate in the presence of proximal stenosis. [PDF]

JA Clin Rep
Sakamoto H, Kitaura A, Tsukimoto S, Yoshino Y, Mino T, Yuasa H, Nakajima Y.   +6 more
europepmc   +1 more source

Bidirectional Mendelian randomization study of brain imaging-derived phenotypes unveils causal associations between thalamic nuclei volume and stroke risk [PDF]

Xuena Yang, Shiyao Cheng, Xingchen Lin, Szu-Hung Lin, Peiyue Su, Xinyao Tang, Jiani Wu, Si Cheng, Siyang Liu   +8 more
openalex   +1 more source