Results 311 to 320 of about 4,500,631 (382)

1151-141 Limitation of stroke volume during dobutamine stress by left ventricular filling time in patients with coronary artery disease

, 2004
Alison Duncan, Derek G. Gibson, Michael Y. Henein   +2 more
openalex   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

Do Acute Diffusion- and Perfusion-Weighted MRI Lesions Identify Final Infarct Volume in Ischemic Stroke?

, 2005
Carly S. Rivers, Joanna M. Wardlaw, Paul A. Armitage, Mark E. Bastin, Trevor Carpenter, Vera Cvoro, Peter J. Hand, Martin Dennis   +7 more
openalex   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

The correlation between carotid artery Doppler and stroke volume during central blood volume loss and resuscitation. [PDF]

Acute Crit Care
Kerrebijn I, Atwi S, Elfarnawany M, Eibl AM, Eibl JK, Taylor JL, Kim CH, Johnson BD, Kenny JS.   +8 more
europepmc   +1 more source

Molecular Creep Induced Fatigue Rupture of Fibrin Clots

Advanced Science, EarlyView.
Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu, Zichang Jia, Binchao Liu, Jizhe Hou, Rui Bao, Mingkun Wang   +5 more
wiley   +1 more source

Cerebral hypometabolism mediates the effect of stroke volume on cognitive impairment in heart failure patients. [PDF]

ESC Heart Fail
Zheng C, Cui Y, Gu S, Yan S, Cui B, Song T, Li J, Si J, Xiao K, Ge Q, Yang Y, Zhou Y, Li J, Li X, Lu J.   +14 more
europepmc   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

Advanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai, Chenyi Yu, Xinyi Luo, Ningyu Xu, Jicheng Yu, Xiao Ye, Yuqi Zhang, Zhen Gu   +7 more
wiley   +1 more source

Effect of systemic vascular resistance on the agreement between stroke volume by non-invasive pulse wave analysis and Doppler ultrasound in healthy volunteers. [PDF]

PLoS One
Lie SL, Hisdal J, Rehn M, Høiseth LØ.
europepmc   +1 more source

A Novel Transfer Learning‐Based Hybrid EEG‐fNIRS Brain‐Computer Interface for Intracerebral Hemorrhage Rehabilitation

Advanced Science, EarlyView.
The study has developed the first clinically validated hybrid EEG‐fNIRS brain‐computer interface fusion framework that systematically overcomes cross‐subject generalization barriers through a novel Wasserstein metric‐driven neural template selection mechanism.
Danyang Chen, Jian Shi, Bo Tao, Xingwei Zhao, Zhixian Zhao, Shengjie Li, Yeguang Xu, Tao Ding, Peng Zhang, Qing Ye, Kuiyou Chen, Zhuojin Wu, Yingxin Tang, Wei Jiang, Kai Shu, Li Huang, Zheng You, Ping Zhang, Zhouping Tang   +18 more
wiley   +1 more source