Results 161 to 170 of about 6,198,727 (341)

Benchmarking Consistency Levels of Cloud-Distributed NoSQL Databases Using YCSB

IEEE Access
Distributed database systems offer scalability and fault tolerance by replicating databases across geographically dispersed nodes. This redundancy aims to ensure data availability even during failures and allows for backups in case of disasters. However,
Saulo Ferreira, Julio Mendonca, Bruno Nogueira, Willy Tiengo, Ermeson Andrade   +4 more
doaj   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

A Proof of Strong Consistency of Maximum Likelihood Estimator for Independent Non-Identically Distributed Data [PDF]

arXiv
We give a general proof of the strong consistency of the Maximum Likelihood Estimator for the case of independent non-identically distributed (i.n.i.d) data, assuming that the density functions of the random variables follow a particular set of assumptions.
arxiv  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Evaluating the Consistency of LLM Evaluators [PDF]

arXiv
Large language models (LLMs) have shown potential as general evaluators along with the evident benefits of speed and cost. While their correlation against human annotators has been widely studied, consistency as evaluators is still understudied, raising concerns about the reliability of LLM evaluators. In this paper, we conduct extensive studies on the
arxiv  

On Strong Consistency of a Stochastic Approximation Algorithm for the Identification of Time-Varying Non-Minimum Phase Systems

, 1985
Marion Hersh
openalex   +1 more source

Strong consistency of a deconvolution estimator of cumulative distribution function

, 2023
Bui Thuy Trang, Cao Xuan Phuong
openalex   +2 more sources

Pivot variables, tests and strong consistency

Qüestiió: quaderns d'estadística i investigació operativa, 1993
Pivot variables, tests and strong consistency.
openaire   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source