Results 191 to 200 of about 419,632 (306)

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Evaluating the performance of AI chatbots in responding to dental implant FAQs: A comparative study. [PDF]

BMC Oral Health
Tuzlalı M, Baki N, Aral K, Aral CA, Bahçe E.   +4 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Consistency Conditions on the Strong Interactions Implied by a Partially Conserved Axial-Vector Current [PDF]

, 1965
Stephen L. Adler
openalex   +1 more source

Peer delivered, emotion regulation-focused mental health prevention training for fire fighter trainees: Design and methodology of a randomized controlled trial. [PDF]

Contemp Clin Trials Commun
Meyer EC, Farchione T, Kimbrel NA, Kwok OM, Pennington ML, Rostockyj J, Gulliver SB.   +6 more
europepmc   +1 more source

Strong consistency of nonparametric Bayes density estimation on compact metric spaces with applications to specific manifolds. [PDF]

Ann Inst Stat Math, 2012
Bhattacharya A, Dunson DB.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Phase consistency test to identify type II strongly lensed gravitational wave signals using a single event [PDF]

Kevin C. Taylor, D. Davis, R. K. L. Lo
openalex   +1 more source

The Strong Uniform Consistency of Nearest Neighbor Density Estimates [PDF]

, 1977
Luc Devroye, T. Wagner
openalex   +1 more source

Research on multiple improvement paths of national innovation output based on tsQCA. [PDF]

PLoS One
Gong Z, Wang X, Li M.
europepmc   +1 more source