Results 41 to 50 of about 543,055 (305)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Strong consistency of regression function estimator with martingale difference errors

open access: yesOpen Mathematics, 2021
In this paper, we consider the regression model with fixed design: Yi=g(xi)+εi{Y}_{i}=g\left({x}_{i})+{\varepsilon }_{i}, 1≤i≤n1\le i\le n, where {xi}\left\{{x}_{i}\right\} are the nonrandom design points, and {εi}\left\{{\varepsilon }_{i}\right\} is a ...
Chen Yingxia
doaj   +1 more source

Multidirectional Replication for Supporting Strong Consistency, Low Latency, and High Throughput

open access: yesAlexandria Engineering Journal, 2022
Many replication protocols, which can be used in various distributed applications such as distributed databases, collaborative applications, and distributed agenda, sacrifice strong consistency to achieve lower latency and higher throughput.
Furat F. Altukhaim   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Pointwise universal consistency of nonparametric linear estimators [PDF]

open access: yes, 2004
This paper presents sufficient conditions for pointwise universal consistency of nonparametric delta estimators.
Vidal-Sanz, Jose M.
core  

Strong laws for weighted sums of widely orthant dependent random variables and applications

open access: yesOpen Mathematics
In this study, the strong law of large numbers and the convergence rate for weighted sums of non-identically distributed widely orthant dependent random variables are established.
Zhu Yong, Wang Wei, Chen Kan
doaj   +1 more source

Strong representation of the Kaplan–Meier and hazard estimators for censored data with m-widely acceptable dependence

open access: yesStatistical Theory and Related Fields
This paper investigates the asymptotic properties of the Kaplan–Meier and hazard estimators for censored survival time data. We conduct this analysis under the assumption of m-widely acceptable (m-WA) dependence, a generalized form of weak correlation ...
Ikhlasse Chebbab
doaj   +1 more source

Asymptotic Properties of Parameter Estimators in Fractional Vasicek Model

open access: yesLithuanian Journal of Statistics, 2016
We consider the fractional Vasicek model of the form dXt = (α-βXt)dt + γdBHt, driven by fractional Brownian motion BH with Hurst parameter H ∈ (0,1). We construct three estimators for an unknown parameter θ=(α,β) and prove their strong consistency.
Stanislav Lohvinenko   +2 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

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