Results 111 to 120 of about 2,257,273 (319)

Strong Coupling‐Induced Topological Edge‐State Laser in 1D High‐Contrast Grating

Advanced Photonics Research
In this study, the lattice constant and filling factor of the 1D high‐contrast grating (HCG) to induce strong coupling and weak coupling between transverse guided modes, to create mode parity transitions, are manipulated.
Hsu‐Chun Hu, Chia‐Jui Chang, Jhih‐Sheng Wu, Tien‐Chang Lu   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

High confinement and high density with stationary plasma energy and strong edge radiation cooling in the upgraded Torus Experiment for Technology Oriented Research (TEXTOR-94) [PDF]

, 1997
A. Messiaen, J. Ongena, B. Unterberg, J.A. Boedo, G. Fuchs, R. Jaspers, L. Könen, H. R. Koslowski, G. Mank, J. Rapp, U. Samm, P. E. Vandenplas, G. Van Oost, G. Van Wassenhove, G. Waidmann, R. Weynants, G.H. Wolf, G. Bertschinger, G. Bonheure, M. Brix, P. Dumortier, F. Durodié, K.H. Finken, B. Giesen, D. L. Hillis, P. Hütteman, R. Koch, A. Krämer-Flecken, A. Lyssoivan, Ph. Mertens, A. Pospieszczyk, A. Post-Zwicker, Markus Sauer, B. Schweer, J. Schwelberger, G. Telesca, M. Z. Tokaŕ, R. Uhlemann, M. Vervier, J. Winter   +39 more
openalex   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

MATCHING AND EDGE COVERING NUMBER ON STRONG PRODUCT OF COMPLETE BIPARTITE GRAPHS [PDF]

, 2014
Thanin Sitthiwirattham
openalex   +1 more source

How strong is strong? The challenge of interpreting network edge weights

PLOS ONE
Weighted networks are information-rich and highly-flexible, but they can be difficult to analyze because the interpretation of edges weights is often ambiguous. Specifically, the meaning of a given edge’s weight is locally contingent, so that a given weight may be strong for one dyad, but weak for other dyad, even in the same network.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Joint Strong Edge and Multi-Stream Adaptive Fusion Network for Non-Uniform Image Deblurring

, 2022
Zihan Li, Guangmang Cui, Jufeng Zhao, Qinlei Xiang, Bintao He   +4 more
openalex   +1 more source