Results 61 to 70 of about 60,228 (248)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Strong edge coloring of subcubic bipartite graphs
, 2013 A strong edge coloring of a graph $G$ is a proper edge coloring in which each color class is an induced matching of $G$. In 1993, Brualdi and Quinn Massey proposed a conjecture that every bipartite graph without $4$-cycles and with the maximum degrees of the two partite sets $2$ and $ $ admits a strong edge coloring with at most $ +2$ colors.
Lužar, Borut +3 more
openaire +2 more sources
Strong Edge Coloring for Channel Assignment in Wireless Radio Networks [PDF]
Fourth Annual IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOMW'06), 2006 We give efficient sequential and distributed approximation algorithms for strong edge coloring graphs modeling wireless networks. Strong edge coloring is equivalent to computing a conflict-free assignment of channels or frequencies to pairwise links between transceivers in the network.
Barrett, C.L. +5 more
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Results in EngineeringA drug molecule can be represented as an isomorphic molecular graph G(V, E), where the atoms form the vertex set V(G) and bonds between atoms constitute the edge set E(G). Topological indices are numerical values computed from isomorphic molecular graphs
C. Yogalakshmi, B. J. Balamurugan
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A note on strong edge-colorings of 2-degenerate graphs
, 2012 We show that every 2-degenerate graph with maximum degree $\Delta$ has a strong edge-coloring with at most $8\Delta-4 ...
Luo, Rong, Yu, Gexin
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source