Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
The 15-Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging. [PDF]
Manoharan MS +30 more
europepmc +1 more source
Lactic Acid Bacteria as Potential Agents for Biocontrol of Aflatoxigenic and Ochratoxigenic Fungi. [PDF]
Mateo EM +3 more
europepmc +1 more source
Strong linear preservers of g-tridiagonal majorization on R^n
Ali Armandnejad, Zahra Gashool
openaire +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
High-precision pothole detection using the ECC-YOLO network with deformable convolution and attention mechanisms. [PDF]
Li H, Zhang C, Ye S.
europepmc +1 more source
Encapsulation of Large-Size Plasmids in PLGA Nanoparticles for Gene Editing: Comparison of Three Different Synthesis Methods. [PDF]
López-Royo T +9 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
EP-YOLO: An Enhanced Lightweight Model for Micro-Pest Detection in Agricultural Light-Trap Environments. [PDF]
Tang Y, Wang J, Sheng W, Bian J.
europepmc +1 more source
An Oral Polyphenol Formulation to Modulate the Ocular Surface Inflammatory Process and to Improve the Symptomatology Associated with Dry Eye Disease. [PDF]
Ng D +9 more
europepmc +1 more source

